It is very exceptional that a new disease becomes a true pandemic. Since its emergence in
Wuhan, China, in late 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), …

Humans are ecosystems containing trillions of microorganisms, but the evolutionary history
of this microbiome is obscured by a lack of knowledge about microbiomes of African apes. …

Plasmodium vivax is the leading cause of human malaria in Asia and Latin America but is
absent from most of central Africa due to the near fixation of a mutation that inhibits the …

Little is known about the clinical features and outcomes of SARS-CoV-2 infection in Africa.
We conducted a retrospective cohort study of patients hospitalized for COVID-19 between …

Metagenomic next-generation sequencing (mNGS), the shotgun sequencing of RNA and
DNA from clinical samples, has proved useful for broad-spectrum pathogen detection and the …

The 10th and largest Ebola virus disease epidemic in the Democratic Republic of the Congo
(DRC) was declared in North Kivu Province in August 2018 and ended in June 2020. We …

Background On May 8, 2018, the Government of the Democratic Republic of the Congo reported
an outbreak of Ebola virus disease in Équateur Province in the northwest of the country. …

Chimpanzees in west central Africa ( Pan troglodytes troglodytes ) are endemically infected
with simian immunodeficiency viruses (SIVcpzPtt) that have crossed the species barrier to …

Background The real-time generation of information about pathogen genomes has become
a vital goal for transmission analysis and characterisation in rapid outbreak responses. In …

Background In 2016, the response to a yellow fever outbreak in Angola and the Democratic
Republic of Congo led to a global shortage of yellow fever vaccine. As a result, a fractional …