The UCSC genome browser database: 2015 update

…, M Haeussler, RA Harte, S Heitner… - Nucleic acids …, 2015 - academic.oup.com
Launched in 2001 to showcase the draft human genome assembly, the UCSC Genome
Browser database ( http://genome.ucsc.edu ) and associated tools continue to grow, providing a …

The UCSC Genome Browser database: extensions and updates 2013

…, K Learned, V Kirkup, F Hsu, S Heitner… - Nucleic acids …, 2012 - academic.oup.com
The University of California Santa Cruz (UCSC) Genome Browser ( http://genome.ucsc.edu )
offers online public access to a growing database of genomic sequence and annotations for …

The UCSC genome browser database: 2014 update

…, M Haeussler, RA Harte, S Heitner… - Nucleic acids …, 2014 - academic.oup.com
The University of California Santa Cruz (UCSC) Genome Browser ( http://genome.ucsc.edu )
offers online public access to a growing database of genomic sequence and annotations for …

The UCSC genome browser database: 2016 update

…, D Karolchik, AS Hinrichs, S Heitner… - Nucleic acids …, 2016 - academic.oup.com
For the past 15 years, the UCSC Genome Browser ( http://genome.ucsc.edu/ ) has served
the international research community by offering an integrated platform for viewing and …

The UCSC genome browser database: 2017 update

…, L Guruvadoo, M Haeussler, S Heitner… - Nucleic acids …, 2017 - academic.oup.com
Since its 2001 debut, the University of California, Santa Cruz (UCSC) Genome Browser (
http://genome.ucsc.edu/ ) team has provided continuous support to the international genomics …

ENCODE data in the UCSC Genome Browser: year 5 update

…, M Maddren, R Fang, SG Heitner… - Nucleic acids …, 2012 - academic.oup.com
The Encyclopedia of DNA Elements (ENCODE), http://encodeproject.org , has completed its
fifth year of scientific collaboration to create a comprehensive catalog of functional elements …

Long-term efficacy and safety of aficamten in patients with symptomatic obstructive hypertrophic cardiomyopathy

…, MA Fifer, SD Solomon, H Watkins, S Heitner… - Journal of the American …, 2023 - jacc.org
Background Aficamten, a next-in-class cardiac myosin inhibitor, decreases myocardial
contractility by reducing myosin-actin interactions in obstructive hypertrophic cardiomyopathy (…

Aficamten in patients with symptomatic non-obstructive hypertrophic cardiomyopathy (REDWOOD-HCM COHORT 4)

…, MA Fifer, SD Solomon, TP Abraham, S Heitner… - Journal of the American …, 2023 - jacc.org
Background Patients with non-obstructive hypertrophic cardiomyopathy (nHCM) represent a
significant subset of HCM patients (~ 30%), and when symptomatic, have few therapeutic …

EFFICACY AND SAFETY OF AFICAMTEN IN THE FIRST COHORT OF PATIENTS WITH SYMPTOMATIC OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY …

…, MA Fifer, SD Solomon, H Watkins, S Heitner… - Journal of the American …, 2024 - jacc.org
Background Aficamten is a next-in-class cardiac myosin inhibitor in development for the
treatment of symptomatic hypertrophic cardiomyopathy (HCM). FOREST-HCM (NCT04848506) …

Mavacamten treatment for obstructive hypertrophic cardiomyopathy: a clinical trial

SB Heitner, D Jacoby, SJ Lester, A Owens… - Annals of internal …, 2019 - acpjournals.org
Background: Mavacamten, an orally administered, small-molecule modulator of cardiac
myosin, targets underlying biomechanical abnormalities in obstructive hypertrophic …