It has become clear that platelets are not simply cell fragments that plug the leak in a damaged
blood vessel; they are, in fact, also key components in the innate immune system, which …

Bacterial adhesion to platelets is mediated via a range of strain-specific bacterial surface
proteins that bind to a variety of platelet receptors. It is unclear how these interactions lead to …

Fibrinogen binding to integrin αIIbβ3 mediates platelet aggregation and requires agonist-induced
“inside-out” signals that increase αIIbβ3 affinity. Agonist regulation of αIIbβ3 also takes …

Endothelial-derived microparticles (EMPs) are a novel biological marker of endothelium injury
and vasomotion disorders that are involved in pathogenesis of cardiovascular, metabolic, …

The ability of Staphylococcus aureus cells to induce platelet aggregation has long been
recognized. However, despite several attempts to identify the mechanisms involved in this …

Osteomyelitis is an inflammatory bone disease that is caused by an infecting microorganism
and leads to progressive bone destruction and loss. The most common causative species …

Electroconductive substrates are emerging as promising functional materials for biomedical
applications. Here, the development of biohybrids of collagen and pristine graphene that …

BACKGROUND & AIMS:: Clinical studies have suggested an association between cardiovascular
disease and infection with Helicobacter pylori. We examined the effect of H. pylori on …

Streptococcus sanguis is the most common oral bacterium causing infective endocarditis and
its ability to adhere to platelets, leading to their activation and aggregation, is thought to be …

Osteomyelitis is a debilitating infectious disease of the bone. It is predominantly caused by S.
aureus and is associated with significant morbidity and mortality. It is characterised by …