Most abundant in the extracellular matrix are collagens, joined by elastin that confers elastic
recoil to the lung, aorta, and skin. These fibrils are highly resistant to proteolysis but can …

The receptor binding and proteolysis of Spike of SARS-CoV-2 release its S 2 subunit to
rearrange and catalyze viral-cell fusion. This deploys the fusion peptide for insertion into the cell …

The forkhead-associated (FHA) domain is a phosphopeptide-binding domain first identified
in a group of forkhead transcription factors but is present in a wide variety of proteins from …

Fluorescence change is convenient for monitoring enzyme kinetics. Unfortunately, it loses
linearity as the absorbance of the fluorescent substrate increases with concentration. When …

Methods are described for producing an active amino‐terminal domain of tissue inhibitor of
metalloproteinases‐1 (N‐TIMP‐1) from inactive protein expressed as inclusion bodies in E. …

Gram‐negative phytopathogenic bacteria, such as Pseudomonas syringae, deliver multiple
effector proteins into plant cells during infection. It is hypothesized that certain plant and …

In plants, light-dependent activation of de novo fatty acid synthesis (FAS) is partially mediated
by acetyl-CoA carboxylase (ACCase), the first committed step for this pathway. However, it …

Photosynthetic bacteria offer excellent experimental opportunities to explore both the
structure and function of the ubiquinol-cytochromec oxidoreductase (bc 1 complex). In …

Matrix metalloproteinases (MMPs) regulate tissue remodelling, inflammation and disease
progression. Some soluble MMPs are inexplicably active near cell surfaces. Here we …

The high-affinity inhibition of stromelysin 1 (MMP-3) by tissue inhibitor of metalloproteinases
1 (TIMP-1) helps control tissue remodeling and tumor development. The interaction of N-…