MouseMine ( www.mousemine.org ) is a new data warehouse for accessing mouse data
from Mouse Genome Informatics (MGI). Based on the InterMine software framework, …

Patient-derived tumor xenograft (PDX) mouse models have emerged as an important oncology
research platform to study tumor evolution, mechanisms of drug response and resistance…

Patient-derived tumor xenograft (PDX) mouse models are a versatile oncology research
platform for studying tumor biology and for testing chemotherapeutic approaches tailored to …

Research using laboratory mice has led to fundamental insights into the molecular genetic
processes that govern cancer initiation, progression, and treatment response. Although …

The Mouse Tumor Biology (MTB; http://tumor.informatics.jax.org ) database is a unique online
compendium of mouse models for human cancer. MTB provides online access to expertly …

Background Patient-derived xenografts (PDX) mice models play an important role in
preclinical trials and personalized medicine. Sharing data on the models is highly valuable for …

The laboratory mouse has served for decades as an informative animal model system for
investigating the genetic and genomic basis of cancer in humans. Although thousands of …

Patient-derived xenografts of lung cancer retain key features observed in the originating
patient tumors and show expected responses to treatment with standard-of-care agents, …

Abstract Model organisms are widely used for understanding basic biology and have
significantly contributed to the study of human disease. In recent years, genomic analysis has …

InterMine is a data integration warehouse and analysis software system developed for large
and complex biological data sets. Designed for integrative analysis, it can be accessed …