[HTML][HTML] EPA, not DHA, prevents fibrosis in pressure overload-induced heart failure: potential role of free fatty acid receptor 4
Heart failure with preserved ejection fraction (HFpEF) is half of all HF, but standard HF therapies
are ineffective. Diastolic dysfunction, often secondary to interstitial fibrosis, is common in …
are ineffective. Diastolic dysfunction, often secondary to interstitial fibrosis, is common in …
Thyroid hormone induces sprouting angiogenesis in adult heart of hypothyroid mice through the PDGF‐Akt pathway
J Chen, SB Ortmeier, OV Savinova… - Journal of cellular …, 2012 - Wiley Online Library
Study of physiological angiogenesis and associated signalling mechanisms in adult heart
has been limited by the lack of a robust animal model. We investigated thyroid hormone‐…
has been limited by the lack of a robust animal model. We investigated thyroid hormone‐…
Collagen has a unique SEC24 preference for efficient export from the endoplasmic reticulum
CL Lu, S Ortmeier, J Brudvig, T Moretti, J Cain… - Traffic, 2022 - Wiley Online Library
SEC24 is mainly involved in cargo sorting during COPII vesicle assembly. There are four
SEC24 paralogs (A–D) in vertebrates, which are classified into two subgroups (SEC24A/B and …
SEC24 paralogs (A–D) in vertebrates, which are classified into two subgroups (SEC24A/B and …
Dietary fish oil modestly attenuates the effect of age on diastolic function but has no effect on memory or brain inflammation in aged rats
…, DR Riddle, FH Chilton, SB Ortmeier… - … Series A: Biomedical …, 2011 - academic.oup.com
Fish oil (FO) mediates a number of cardioprotective benefits in patients with cardiovascular
disease. In the absence of cardiovascular disease, however, the effects of FO on cardiac …
disease. In the absence of cardiovascular disease, however, the effects of FO on cardiac …
[BOOK][B] A comparison of two soybean (Glycine max, L.) lines for flood tolerance mechanisms
SB Ortmeier - 2003 - search.proquest.com
Flooding, excess water in the root environment of land plants, can be injurious or lethal to
plants due to blocking of oxygen transfer and other gases between root, soil, and atmosphere. …
plants due to blocking of oxygen transfer and other gases between root, soil, and atmosphere. …
Novel Cardiac Dyssynchrony Metrics Based on Ultrasound Images and Fibrosis
…, T Hanson, J Eclov, S Courtier, S Ortmeier… - Circulation …, 2015 - Am Heart Assoc
Ventricular stiffening is a component of heart failure with preserved ejection fraction. This
study focuses on building a dyssynchrony metric based on ultrasound images obtained from …
study focuses on building a dyssynchrony metric based on ultrasound images obtained from …
[HTML][HTML] Reduced apolipoprotein glycosylation in patients with the metabolic syndrome
OV Savinova, K Fillaus, L Jing, WS Harris, GC Shearer - PloS one, 2014 - journals.plos.org
Objective The purpose of this study was to compare the apolipoprotein composition of the
three major lipoprotein classes in patients with metabolic syndrome to healthy controls. …
three major lipoprotein classes in patients with metabolic syndrome to healthy controls. …
Effects of niacin and omega-3 fatty acids on the apolipoproteins in overweight patients with elevated triglycerides and reduced HDL cholesterol
OV Savinova, K Fillaus, WS Harris, GC Shearer - Atherosclerosis, 2015 - Elsevier
… We thank Steven Ortmeier and Vijaya Nareddy for technical assistance in apo quantification.
We acknowledge the use of proteomics facilities at Sanford-Burnham Institute for Medical …
We acknowledge the use of proteomics facilities at Sanford-Burnham Institute for Medical …
[CITATION][C] Optimized dual promoter AAV gene therapy for lysosomal β-glucocerebrosidase with high M6P content for treatment of neuronopathic Gaucher disease
A Hedman, SB Ortmeier, S Liu, J Srnak, Y Zhao… - Molecular Genetics and …, 2024 - Elsevier
[CITATION][C] Highly phosphorylated β-glucocerebrosidase (M011) that targets central nervous system neurons as a potential treatment for neuronopathic Gaucher …
M DiGruccio, SB Ortmeier, U Wanninayake… - Molecular Genetics and …, 2023 - Elsevier