[HTML][HTML] Parkinson's disease therapeutics: new developments and challenges since the introduction of levodopa

Y Smith, T Wichmann, SA Factor… - …, 2012 - nature.com
The demonstration that dopamine loss is the key pathological feature of Parkinson's disease
(PD), and the subsequent introduction of levodopa have revolutionalized the field of PD …

Parkinson's disease: diagnosis and clinical management

SA Factor, WJ Weiner - 2007 - books.google.com
Parkinson's disease (PD) is the second most common neurodegenerative disease in the
world. Still the only major text on the subject, the completely revised and updated second …

Atypical antipsychotics in the treatment of drug-induced psychosis in Parkinson's disease.

JH Friedman, SA Factor - Movement disorders: official journal of the …, 2000 - europepmc.org
Our experience with atypical antipsychotics in patients with PD is that their motor effects are
not predictable. The multiple reports concerning clozapine's beneficial effects on tremor, …

Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease

…, A Griffith, A Samii, WK Scott, J Nutt, SA Factor… - Nature …, 2010 - nature.com
Parkinson's disease is a common disorder that leads to motor and cognitive disability. We
performed a genome-wide association study of 2,000 individuals with Parkinson's disease (…

Parkinson's disease and Parkinson's disease medications have distinct signatures of the gut microbiome

…, ZD Wallen, SD Peddada, SA Factor… - Movement …, 2017 - Wiley Online Library
Background There is mounting evidence for a connection between the gut and Parkinson's
disease (PD). Dysbiosis of gut microbiota could explain several features of PD. Objective The …

[HTML][HTML] Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database

…, AL DeStefano, CB Do, N Eriksson, SA Factor… - PLoS …, 2012 - journals.plos.org
More than 800 published genetic association studies have implicated dozens of potential
risk loci in Parkinson's disease (PD). To facilitate the interpretation of these findings, we have …

Sleep disorders and sleep effect in Parkinson's disease

SA Factor, T McAlarney… - … : official journal of the …, 1990 - Wiley Online Library
It has been suggested that sleep may have a positive effect on morning motor symptoms in
Parkinson's disease (PD). We examined this possibility and also looked at common sleep …

CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion

…, EA Epping, D Erickson, C Erwin, K Evans, SA Factor… - Neurology, 2012 - AAN Enterprises
… but also the predominant factor determining the rate of the … on age at onset, other cis-factors
may play a role in modifying … role for other cis-factors in potentially modifying age at onset …

Psychogenic movement disorders: frequency, clinical profile, and characteristics.

SA Factor, GD Podskalny, ES Molho - Journal of Neurology …, 1995 - jnnp.bmj.com
Of 842 consecutive patients with movement disorders seen over a 71 month period, 28 (3.3%)
were diagnosed as having a documented or clinically established psychogenic movement …

Occupation and risk of parkinsonism: a multicenter case-control study

…, RA Hauser, J Jankovic, SA Factor… - Archives of …, 2009 - jamanetwork.com
Background We examined risk of parkinsonism in occupations (agriculture, education, health
care, welding, and mining) and toxicant exposures (solvents and pesticides) putatively …