User profiles for Stuart T. Johnston
 | Stuart JohnstonSenior Lecturer, University of Melbourne Verified email at unimelb.edu.au Cited by 778 |
[HTML][HTML] Estimating cell diffusivity and cell proliferation rate by interpreting IncuCyte ZOOM™ assay data using the Fisher-Kolmogorov model
Background Standard methods for quantifying IncuCyte ZOOM™ assays involve measurements
that quantify how rapidly the initially-vacant area becomes re-colonised with cells as a …
that quantify how rapidly the initially-vacant area becomes re-colonised with cells as a …
Self-assembly of nano-to macroscopic metal–phenolic materials
The self-assembly of molecular building blocks into well-defined macroscopic materials is
desirable for developing emergent functional materials. However, the self-assembly of …
desirable for developing emergent functional materials. However, the self-assembly of …
How much information can be obtained from tracking the position of the leading edge in a scratch assay?
ST Johnston, MJ Simpson… - Journal of the Royal …, 2014 - royalsocietypublishing.org
Moving cell fronts are an essential feature of wound healing, development and disease. The
rate at which a cell front moves is driven, in part, by the cell motility, quantified in terms of the …
rate at which a cell front moves is driven, in part, by the cell motility, quantified in terms of the …
[HTML][HTML] Co-operation, competition and crowding: a discrete framework linking Allee kinetics, nonlinear diffusion, shocks and sharp-fronted travelling waves
Invasion processes are ubiquitous throughout cell biology and ecology. During invasion,
individuals can become isolated from the bulk population and behave differently. We present a …
individuals can become isolated from the bulk population and behave differently. We present a …
Quantifying the effect of experimental design choices for in vitro scratch assays
Scratch assays are often used to investigate potential drug treatments for chronic wounds
and cancer. Interpreting these experiments with a mathematical model allows us to estimate …
and cancer. Interpreting these experiments with a mathematical model allows us to estimate …
Mean-field descriptions of collective migration with strong adhesion
Random walk models based on an exclusion process with contact effects are often used to
represent collective migration where individual agents are affected by agent-to-agent …
represent collective migration where individual agents are affected by agent-to-agent …
Interpreting scratch assays using pair density dynamics and approximate Bayesian computation
Quantifying the impact of biochemical compounds on collective cell spreading is an essential
element of drug design, with various applications including developing treatments for …
element of drug design, with various applications including developing treatments for …
An analytical approach for quantifying the influence of nanoparticle polydispersity on cellular delivered dose
ST Johnston, M Faria… - Journal of The Royal …, 2018 - royalsocietypublishing.org
Nanoparticles provide a promising approach for the targeted delivery of therapeutic, diagnostic
and imaging agents in the body. However, it is not yet fully understood how the physico-…
and imaging agents in the body. However, it is not yet fully understood how the physico-…
Selective metal–phenolic assembly from complex multicomponent mixtures
Selective self-assembly in multicomponent mixtures offers a method for isolating desired
components from complex systems for the rapid production of functional materials. Developing …
components from complex systems for the rapid production of functional materials. Developing …
[HTML][HTML] Spatio-temporal analysis of nanoparticles in live tumor spheroids impacted by cell origin and density
Nanoparticles hold great preclinical promise in cancer therapy but continue to suffer attrition
through clinical trials. Advanced, three dimensional (3D) cellular models such as tumor …
through clinical trials. Advanced, three dimensional (3D) cellular models such as tumor …