Epileptogenic triggers are multifactorial and not well understood. Here we aimed to address
the hypothesis that inappropriate pro-inflammatory mechanisms contribute to the …

Background There is limited information on the functional neutralizing capabilities of breastmilk
SARS-CoV-2-specific antibodies and the potential adulteration of breastmilk with vaccine …

We studied whether blockade of inhibitory receptors on cytokine-induced killer (CIK) cells
by immune checkpoint inhibitors could increase its anti-tumour potency against …

To the Editor—The proliferation of single-cell datasets from mass cytometry has driven the
need for an open registry capable of hosting data from different laboratories, correcting for …

Drug refractory epilepsy (RE) is a chronic neurological disease with varied etiology that
represents a group of patients whose seizures do not respond to antiepileptic drugs. The …

Objectives Immunogenicity to the SARS-CoV-2 mRNA vaccines in adolescents and young
adults (AYA) with childhood-onset rheumatic diseases (cRD) is unknown. We aimed to …

Chronic heart failure (HF) is a syndrome of heterogeneous etiology associated with multiple
co-morbidities. Inflammation is increasingly recognized as a key contributor to the …

Objectives Biologics treatment with antitumour necrosis factor alpha (TNFα) is efficacious in
patients with juvenile idiopathic arthritis (JIA). Despite displaying clinical inactivity during …

An accurate depiction of the convalescent COVID-19 immunome will help delineate the
immunological milieu crucial for disease resolution and protection. Using mass cytometry, we …

Objectives To evaluate the humoral immunogenicity for 6 months after the two-dose
coronavirus disease 2019 (COVID-19) mRNA vaccination in adolescents and young adults (AYAs) …