Clonal interference, the competition between lineages arising from different beneficial
mutations in an asexually reproducing population, is an important factor determining the tempo …

Recent experimental and theoretical studies have shown that small asexual populations
evolving on complex fitness landscapes may achieve a higher fitness than large ones due to …

The adaptation of large asexual populations is hampered by the competition between
independently arising beneficial mutations in different individuals, which is known as clonal …

The nature of epistasis has important consequences for the evolutionary significance of sex
and recombination. Recent efforts to find negative epistasis as a source of negative linkage …

The pair contact process with diffusion (PCPD) has been recently investigated extensively,
but its critical behavior is not yet clearly established. By introducing biased diffusion, we show …

We consider an asexual biological population of constant size N evolving in discrete time
under the influence of selection and mutation. Beneficial mutations appear at rate U and their …

Quantifying the dynamics of intrahost HIV-1 sequence evolution is one means of uncovering
information about the interaction between HIV-1 and the host immune system. In the chronic …

We present a formalism to derive the stochastic differential equations (SDEs) for several
solid-on-solid growth models. Our formalism begins with a mapping of the microscopic …

In his celebrated model of adaptation, Fisher assumed a smooth phenotype fitness map with
one optimum. This assumption is at odds with the rugged..... Fisher’s geometric model was …

We consider the evolution of an asexually reproducing population in an uncorrelated random
fitness landscape in the limit of infinite genome size, which implies that each mutation …