Estimating familial cancer risks is clinically important in being able to discriminate between
individuals in the population at differing risk for malignancy. To gain insight into the familial …

Improvement of survival in lymphocytic leukaemia has been accompanied by the occurrence
of second primary cancer (SPCs). Based on Swedish Family Cancer Database, we applied …

Myeloid malignancies are clonal proliferative diseases with shared but diverse phenotype
characteristics; this classification includes (1) the myeloproliferative neoplasms (MPNs), …

Purpose: While patients with intermediate-risk (IR) Wilms tumors now have an overall survival
(OS) rate of almost 90%, those affected by high-stage tumors with diffuse anaplasia have …

While treatment for testicular cancer (TC) has become standardized after the 1980s with an
associated significant improvement in patient survival, this has been accompanied by an …

Multiple myeloma (MM) is an incurable disease characterized by the presence of malignant
plasma cells in the bone marrow that secrete specific monoclonal immunoglobulins into the …

Second primary cancers (SPCs) account for an increasing proportion of all cancer diagnoses.
It is unlikely that prior therapy is solely responsible for SPC risk. To investigate risk of SPC …

A mathematical model of eco-evolutionary dynamics estimates different birth rates of cells at
the periphery of a tumour versus its centre, giving insight into locally stable evolutionary …

Phylogenetic reconstruction of cancer cell populations remains challenging. There is a
particular lack of tools that deconvolve clones based on copy number aberration analyses of …

Second primary cancers (SPCs) account for an increasing proportion of all cancer diagnoses
and family history of cancer may be a risk factor for SPCs. Using the Swedish Family‐…