User profiles for Suchandrima Saha
 | Suchandrima Saha, PhDResearch Scientist Verified email at stonybrookmedicine.edu Cited by 469 |
Exogenous and endogenous sources of serine contribute to colon cancer metabolism, growth, and resistance to 5-fluorouracil
… Suchandrima Saha; Suchandrima Saha … Montrose, Suchandrima Saha, Miguel Foronda,
Erin M. McNally, Justin Chen, Xi Kathy Zhou, Taehoon Ha, Jan Krumsiek, Mustafa Buyukozkan, …
Erin M. McNally, Justin Chen, Xi Kathy Zhou, Taehoon Ha, Jan Krumsiek, Mustafa Buyukozkan, …
[HTML][HTML] Inhibition of USP2 eliminates cancer stem cells and enhances TNBC responsiveness to chemotherapy
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer that
harbors enriched cancer stem cell (CSC) populations in tumors. Conventional chemotherapy …
harbors enriched cancer stem cell (CSC) populations in tumors. Conventional chemotherapy …
[PDF][PDF] Mutant p53 suppresses innate immune signaling to promote tumorigenesis
Mutant p53 (mtp53) proteins can exert cancer-promoting gain-of-function activities. We
report a mechanism by which mtp53 suppresses both cell-autonomous and non-cell-autonomous …
report a mechanism by which mtp53 suppresses both cell-autonomous and non-cell-autonomous …
[PDF][PDF] p53 engages the cGAS/STING cytosolic DNA sensing pathway for tumor suppression
Tumor suppression by TP53 involves cell-autonomous and non-cell-autonomous mechanisms.
TP53 can suppress tumor growth by modulating immune system functions; however, the …
TP53 can suppress tumor growth by modulating immune system functions; however, the …
Synthesis, characterization and cytotoxicity of europium incorporated ZnO–graphene nanocomposites on human MCF7 breast cancer cells
Europium incorporated ZnO-chemically converted graphene (CCG) nanocomposites (ZEG)
were synthesized by adopting a solvothermal process at 95 C from the precursors of varying …
were synthesized by adopting a solvothermal process at 95 C from the precursors of varying …
[HTML][HTML] A potent tumoricidal co-drug 'Bet-CA'-an ester derivative of betulinic acid and dichloroacetate selectively and synergistically kills cancer cells
Selective targeting of cancer cells employing multiple combinations as co-drug holds promise
for new generation therapeutics. Betulinic acid (BA), a plant secondary metabolite kills …
for new generation therapeutics. Betulinic acid (BA), a plant secondary metabolite kills …
Induction and evaluation of murine colitis induced by T cell transfer
Inflammatory bowel diseases (IBD) involve repetitive bouts of inflammation in the intestinal
tract and can result in severe morbidity for patients. Moreover, long-standing IBD increases …
tract and can result in severe morbidity for patients. Moreover, long-standing IBD increases …
Serine Supports Epithelial and Immune Cell Function in Colitis
Inflammatory bowel diseases (IBD) are chronic inflammatory disorders of the gastrointestinal
tract that are largely driven by immune cell activity, while mucosal healing is critical for …
tract that are largely driven by immune cell activity, while mucosal healing is critical for …
[HTML][HTML] Role of metabolic modulator Bet-CA in altering mitochondrial hyperpolarization to suppress cancer associated angiogenesis and metastasis
Solid tumors characteristically reflect a metabolic switching from glucose oxidation to
glycolysis that plays a fundamental role in angiogenesis and metastasis to facilitate aggressive …
glycolysis that plays a fundamental role in angiogenesis and metastasis to facilitate aggressive …
'Dual hit'metabolic modulator LDCA selectively kills cancer cells by efficient competitive inhibition of LDH-A
Herein, we synthesize and elucidate the potential of a novel ‘dual hit’ molecule, LDCA, to
constitutively block lactate dehydrogenase isoform-A (LDH-A) to selectively subvert apoptosis …
constitutively block lactate dehydrogenase isoform-A (LDH-A) to selectively subvert apoptosis …