[HTML][HTML] Multiple female reproductive failures in cyclooxygenase 2–deficient mice
…, JE Dinchuk, R Langenbach, JM Trzaskos, SK Dey - Cell, 1997 - cell.com
Cyclooxygenase (COX) is the rate-limiting enzyme in the synthesis of prostaglandins (PGs)
and exists in two isoforms, COX-1 and COX-2. In spite of long-standing speculation, definitive …
and exists in two isoforms, COX-1 and COX-2. In spite of long-standing speculation, definitive …
Mechanisms of implantation: strategies for successful pregnancy
Physiological and molecular processes initiated during implantation for pregnancy success
are complex but highly organized. This review primarily highlights adverse ripple effects …
are complex but highly organized. This review primarily highlights adverse ripple effects …
[PDF][PDF] CXCR2-expressing myeloid-derived suppressor cells are essential to promote colitis-associated tumorigenesis
H Katoh, D Wang, T Daikoku, H Sun, SK Dey… - Cancer cell, 2013 - cell.com
A large body of evidence indicates that chronic inflammation is one of several key risk factors
for cancer initiation, progression, and metastasis. However, the underlying mechanisms …
for cancer initiation, progression, and metastasis. However, the underlying mechanisms …
Preterm labor: one syndrome, many causes
Preterm birth is associated with 5 to 18% of pregnancies and is a leading cause of infant
morbidity and mortality. Spontaneous preterm labor, a syndrome caused by multiple pathologic …
morbidity and mortality. Spontaneous preterm labor, a syndrome caused by multiple pathologic …
Roadmap to embryo implantation: clues from mouse models
H Wang, SK Dey - Nature Reviews Genetics, 2006 - nature.com
Implantation involves an intricate discourse between the embryo and uterus and is a
gateway to further embryonic development. Synchronizing embryonic development until the …
gateway to further embryonic development. Synchronizing embryonic development until the …
[HTML][HTML] Host cyclooxygenase-2 modulates carcinoma growth
Cyclooxygenase-2 (COX-2; Ptgs2) acts as a tumor promoter in rodent models for colorectal
cancer, but its precise role in carcinogenesis remains unclear. We evaluated the contribution …
cancer, but its precise role in carcinogenesis remains unclear. We evaluated the contribution …
Heparin-binding EGF-like growth factor gene is induced in the mouse uterus temporally by the blastocyst solely at the site of its apposition: a possible ligand for …
…, M Klagsbrun, GK Andrews, SK Dey - …, 1994 - journals.biologists.com
Heparin-binding EGF-like growth factor (HB-EGF) is a newly discovered member of the EGF
family of growth factors. HB-EGF can bind to two loci on cell surfaces, heparan sulphate …
family of growth factors. HB-EGF can bind to two loci on cell surfaces, heparan sulphate …
Endocannabinoid signaling at the periphery: 50 years after THC
In 1964, the psychoactive ingredient of Cannabis sativa, Δ 9 -tetrahydrocannabinol (THC),
was isolated. Nearly 30 years later the endogenous counterparts of THC, collectively termed …
was isolated. Nearly 30 years later the endogenous counterparts of THC, collectively termed …
Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARδ
We have demonstrated previously that cyclo-oxygenase-2 (COX2), the rate-limiting enzyme
in the biosynthesis of prostaglandins (PGs), is essential for blastocyst implantation and …
in the biosynthesis of prostaglandins (PGs), is essential for blastocyst implantation and …
Estrogen is a critical determinant that specifies the duration of the window of uterine receptivity for implantation
Many underlying causes of human infertility have been overcome by using in vitro fertilization
(IVF) and embryo transfer (ET) techniques. Nevertheless, implantation rates in IVF …
(IVF) and embryo transfer (ET) techniques. Nevertheless, implantation rates in IVF …