Epstein-Barr virus (EBV) has been associated with several types of human cancers. In the
host, EBV can establish two alternative modes of life cycle, known as latent or lytic and the …

Background Multiple myeloma (MM) is a hematologic cancer caused by the abnormal
expansion of plasma cells, but the exact mechanism underlying MM development is not …

Icaritin is an active prenylflavonoid derived from Epimedium genus, a traditional Chinese
medicine. Icaritin has a wide range of pharmacological and biological activities, including …

Pain, especially when chronic, is a common reason patients seek medical care and it affects
the quality of life and well-being of the patients. Unfortunately, currently available therapies …

Epstein–Barr virus (EBV) reactivation into the lytic cycle plays certain roles in the development
of EBV-associated diseases, including nasopharyngeal carcinoma and lymphoma. In this …

Migraine is one of the most disabling neurological diseases worldwide; however, the
mechanisms underlying migraine headache are still not fully understood and current therapies for …

Neuropathic pain represents a challenge to clinicians because it is resistant to commonly
prescribed analgesics due to its largely unknown mechanisms. Here, we investigated a …

Patients with temporomandibular disorders (TMDs) often experience persistent facial pain.
However, the treatment of TMD pain is still inadequate. In recent years, the disturbance of gut …

BACKGROUND: Primary Sjögren's syndrome (pSS) is an autoimmune disease characterized
by lymphocytic infiltration and the production of autoantibodies, leading to the destruction …

In recent years, the high-speed urbanization process and human activities have led to the
fragmentation and the connectivity reduction of natural landscape patches, resulting in the …