[HTML][HTML] Extensive gut virome variation and its associations with host and environmental factors in a population-level cohort
S Nishijima, N Nagata, Y Kiguchi, Y Kojima… - Nature …, 2022 - nature.com
Indigenous bacteriophage communities (virome) in the human gut have a huge impact on
the structure and function of gut bacterial communities (bacteriome), but virome variation at a …
the structure and function of gut bacterial communities (bacteriome), but virome variation at a …
The gut microbiome of healthy Japanese and its microbial and functional uniqueness
The human gut microbiome has profound influences on the host's health largely through its
interference with various intestinal functions. As recent studies have suggested diversity in …
interference with various intestinal functions. As recent studies have suggested diversity in …
[HTML][HTML] Population-level metagenomics uncovers distinct effects of multiple medications on the human gut microbiome
N Nagata, S Nishijima, T Miyoshi-Akiyama, Y Kojima… - Gastroenterology, 2022 - Elsevier
Background & aims Medication is a major determinant of human gut microbiome structure,
and its overuse increases the risks of morbidity and mortality. However, effects of certain …
and its overuse increases the risks of morbidity and mortality. However, effects of certain …
[HTML][HTML] Long-read metagenomic exploration of extrachromosomal mobile genetic elements in the human gut
Background Elucidating the ecological and biological identity of extrachromosomal mobile
genetic elements (eMGEs), such as plasmids and bacteriophages, in the human gut remains …
genetic elements (eMGEs), such as plasmids and bacteriophages, in the human gut remains …
[HTML][HTML] Nitrogen fixation and nifH diversity in human gut microbiota
It has been hypothesized that nitrogen fixation occurs in the human gut. However, whether
the gut microbiota truly has this potential remains unclear. We investigated the nitrogen-fixing …
the gut microbiota truly has this potential remains unclear. We investigated the nitrogen-fixing …
[HTML][HTML] Metagenomic identification of microbial signatures predicting pancreatic cancer from a multinational study
N Nagata, S Nishijima, Y Kojima, Y Hisada, K Imbe… - Gastroenterology, 2022 - Elsevier
Background & Aims To identify gut and oral metagenomic signatures that accurately predict
pancreatic ductal carcinoma (PDAC) and to validate these signatures in independent cohorts…
pancreatic ductal carcinoma (PDAC) and to validate these signatures in independent cohorts…
[HTML][HTML] Effects of bowel preparation on the human gut microbiome and metabolome
N Nagata, M Tohya, S Fukuda, W Suda, S Nishijima… - Scientific reports, 2019 - nature.com
Large bowel preparation may cause a substantial change in the gut microbiota and metabolites.
Here, we included a bowel prep group and a no-procedure control group and evaluated …
Here, we included a bowel prep group and a no-procedure control group and evaluated …
Circadian oscillations of microbial and functional composition in the human salivary microbiome
…, C Shindo, Y Hattori, N Yamashita, S Nishijima… - DNA …, 2017 - academic.oup.com
The human microbiomes across the body evidently interact with various signals in response
to biogeographical physiological conditions. To understand such interactions in detail, we …
to biogeographical physiological conditions. To understand such interactions in detail, we …
[HTML][HTML] Revealing the microbial assemblage structure in the human gut microbiome using latent Dirichlet allocation
Background The human gut microbiome has been suggested to affect human health and thus
has received considerable attention. To clarify the structure of the human gut microbiome, …
has received considerable attention. To clarify the structure of the human gut microbiome, …
Long-read metagenomics of multiple displacement amplified DNA of low-biomass human gut phageomes by SACRA pre-processing chimeric reads
The human gut bacteriophage community (phageome) plays an important role in the host’s
health and disease; however, the entire structure is poorly understood, partly owing to the …
health and disease; however, the entire structure is poorly understood, partly owing to the …