Background Several cell lines and primary cultures benefit from the use of positively charged
extracellular matrix proteins or polymers that enhance their ability to attach to culture plates…

The RNA-binding proteins involved in regulation of mRNA post-transcriptional processing and
translation control the fates of thousands of mRNA transcripts and basic cellular processes…

Human antigen R (HuR) is an RNA-binding protein with protective activities against cellular
stress. This study considers the mechanisms by which HuR transcriptional regulation occurs …

Human antigen R (HuR) is a post‐transcriptional regulator of gene expression that plays a
key role in stabilizing mRNAs during cellular stress, leading to enhanced survival. HuR …

Radiation therapy for abdominal tumors is challenging because the small intestine is
exquisitely radiosensitive. Unfortunately, there are no FDA-approved therapies to prevent or …

Pancreatic cancer is a highly lethal disease whose aggressive biology that is driven by
mitochondrial oxidative metabolism. Mitochondria normally form a network of fused organelles, …

Background/Aims: HuR is an RNA-binding protein that regulates the post-transcriptional life
of thousands of cellular mRNAs and promotes cell survival. HuR is expressed as two mRNA …

Teleost fish show a remarkable capability of nerve regeneration in their CNS, while injuries
to axon fibers in the CNS of mammals result in degeneration and loss of function. …

Mammals do not regenerate axons in their central nervous system (CNS) spontaneously. This
phenomenon is the cause of numerous medical conditions after damage to nerve fibers in …

Metastasis is a defining feature of pancreatic cancer, impacting patient quality of life and
therapeutic outcomes. While recurrent mutations in KRAS and TP53 play important roles in …