Current vaccine strategies against the asexual blood stage of Plasmodium falciparum are
mostly focused on well-studied merozoite antigens that induce immune responses after …

Virus-like particles (VLPs) are non-infectious self-assembling nanoparticles, useful in
medicine and nanotechnology. Their repetitive molecularly-defined architecture is attractive for …

There are no licensed vaccines against Plasmodium vivax. We conducted two phase 1/2a
clinical trials to assess two vaccines targeting P. vivax Duffy-binding protein region II (PvDBPII)…

Authorized vaccines against SARS-CoV-2 remain less available in low- and middle-income
countries due to insufficient supply, high costs, and storage requirements. Global immunity …

The induction of cellular immunity, in conjunction with antibodies, may be essential for
vaccines to protect against blood-stage infection with the human malaria parasite Plasmodium …

Background Traditionally, vaccine development against the blood-stage of Plasmodium
falciparum infection has focused on recombinant protein-adjuvant formulations in order to …

The standard membrane feeding assay (SMFA) is currently considered to be the ‘gold standard’
for assessing the effectiveness of malaria transmission blocking interventions (TBIs) in …

Plasmodium parasites are the causative agent of human malaria, and the development of a
highly effective vaccine against infection, disease and transmission remains a key priority. It …

The development of a highly effective vaccine remains a key strategic goal to aid the control
and eventual eradication of Plasmodium falciparum malaria. In recent years, the reticulocyte-…

Engineering modular platforms to control biomolecular architecture can advance both the
understanding and the manipulation of biological systems. Icosahedral particles uniformly …