User profiles for Sumita Chakraborty

Sumita Chakraborty

Postdoctoral Fellow, Weizmann Institute of Science
Verified email at weizmann.ac.il
Cited by 305

[HTML][HTML] Glucose oxidase from Aspergillus niger. Cloning, gene sequence, secretion from Saccharomyces cerevisiae and kinetic analysis of a yeast-derived enzyme.

…, A Vasavada, S Rosenberg, S Chakraborty… - Journal of Biological …, 1990 - Elsevier
The gene for Aspergillus niger glucose oxidase (EC 1.1.3.4) has been cloned from both
cDNA and genomic libraries using oligonucleotide probes derived from the amino acid …

Old yellow enzyme: aromatization of cyclic enones and the mechanism of a novel dismutation reaction

ADN Vaz, S Chakraborty, V Massey - Biochemistry, 1995 - ACS Publications
Revised Manuscript Received January 19, 1995® abstract: The origin of charge transfer bands
that develop on reaction of Old Yellow Enzyme with,/3-unsaturated cyclic ketonessuch as …

[HTML][HTML] A New Old Yellow Enzyme of Saccharomyces cerevisiae (∗)

YS Niino, S Chakraborty, BJ Brown… - Journal of Biological …, 1995 - ASBMB
In 1993, the first gene of Old Yellow Enzyme (OYE) of Saccharomyces cerevisiae was cloned
(Stott, K., Saito, K., Thiele, DJ, and Massey, V.(1993) J. Biol. Chem. 268, 6097-6106) and …

Protein refolding by pH-triggered chaperone binding and release

…, TM Franzmann, S Chakraborty… - Proceedings of the …, 2010 - National Acad Sciences
Molecular chaperones are typically either adenosine triphosphate (ATP) dependent or rely
heavily on their ATP-dependent chaperone counterparts in order to promote protein folding. …

[PDF][PDF] Choline is an intracellular messenger linking extracellular stimuli to IP3-evoked Ca2+ signals through sigma-1 receptors

E Brailoiu, S Chakraborty, GC Brailoiu, P Zhao, JL Barr… - Cell reports, 2019 - cell.com
Sigma-1 receptors (Sig-1Rs) are integral ER membrane proteins. They bind diverse ligands,
including psychoactive drugs, and regulate many signaling proteins, including the inositol 1,…

Telomere length is associated with types of chromosome 21 nondisjunction: a new insight into the maternal age effect on Down syndrome birth

S Ghosh, E Feingold, S Chakraborty, SK Dey - Human genetics, 2010 - Springer
Advanced maternal age is a well-documented risk factor of chromosome 21 nondisjunction
in humans, but understanding of this association at the genetic level is still limited. In …

Impact of malnutrition on survival and healthcare utilization in Medicare beneficiaries with diabetes: a retrospective cohort analysis

N Ahmed, Y Choe, VA Mustad, S Chakraborty… - BMJ Open Diabetes …, 2018 - drc.bmj.com
Objective The aim of this study was to examine the impact of pre-existing malnutrition on
survival and economic implications in elderly patients with diabetes. Research design and …

Studies on the Mechanism of p-Hydroxyphenylacetate 3-Hydroxylase from Pseudomonas aeruginosa: A System Composed of a Small Flavin Reductase and a …

S Chakraborty, M Ortiz-Maldonado, B Entsch… - Biochemistry, 2010 - ACS Publications
There are two known types of microbial two-component flavin-dependent monooxygenases
that catalyze oxygenation of p-hydroxyphenylacetate (HPA), and they are distinguished by …

GPN does not release lysosomal Ca2+ but evokes Ca2+ release from the ER by increasing the cytosolic pH independently of cathepsin C

…, M Apta-Smith, S Chakraborty… - Journal of cell …, 2019 - journals.biologists.com
The dipeptide glycyl-l-phenylalanine 2-naphthylamide (GPN) is widely used to perturb
lysosomes because its cleavage by the lysosomal enzyme cathepsin C is proposed to rupture …

APOE4 affects basal and NMDAR-mediated protein synthesis in neurons by perturbing calcium homeostasis

…, SC Konings, B Nawalpuri, S Chakraborty… - Journal of …, 2021 - Soc Neuroscience
Apolipoprotein E (APOE), one of the primary lipoproteins in the brain has three isoforms in
humans, APOE2, APOE3, and APOE4. APOE4 is the most well-established risk factor …