Serum amyloid A delivers retinol to intestinal myeloid cells to promote adaptive immunity

YJ Bang, Z Hu, Y Li, S Gattu, KA Ruhn, P Raj, J Herz… - Science, 2021 - science.org
INTRODUCTION Vitamin A is a lipid-soluble nutrient that is absorbed from the diet by intestinal
epithelial cells and converted to retinol. This product of vitamin A metabolism is essential …

Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection

MG Derebe, CM Zlatkov, S Gattu, KA Ruhn… - Elife, 2014 - elifesciences.org
10.7554/eLife.03206.001 Retinol plays a vital role in the immune response to infection, yet
proteins that mediate retinol transport during infection have not been identified. Serum …

Epidemiology and risk factors for isolation of Escherichia coli producing CTX-M-type extended-spectrum β-lactamase in a large US medical center

K Hayakawa, S Gattu, D Marchaim… - Antimicrobial agents …, 2013 - Am Soc Microbiol
A case-case-control study was conducted to identify independent risk factors for recovery of
Escherichia coli strains producing CTX-M-type extended-spectrum β-lactamases (CTX-M E. …

[PDF][PDF] Resistin-like molecule α provides vitamin-A-dependent antimicrobial protection in the skin

TA Harris, S Gattu, DC Propheter, Z Kuang, S Bel… - Cell host & …, 2019 - cell.com
Vitamin A deficiency increases susceptibility to skin infection. However, the mechanisms by
which vitamin A regulates skin immunity remain unclear. Here, we show that resistin-like …

Epithelial retinoic acid receptor β regulates serum amyloid A expression and vitamin A-dependent intestinal immunity

S Gattu, YJ Bang, M Pendse, C Dende… - Proceedings of the …, 2019 - National Acad Sciences
Vitamin A is a dietary component that is essential for the development of intestinal immunity.
Vitamin A is absorbed and converted to its bioactive derivatives retinol and retinoic acid by …

[PDF][PDF] EPITHELIAL RETINOIC ACID RECEPTOR BETA REGULATES SERUM AMYLOID A EXPRESSION AND VITAMIN A-DEPENDENT INTESTINAL IMMUNITY

LV Hooper, S Winter, SA Kliewer, M Shiloh - utswmed-ir.tdl.org
… Rajkumar Gattu, for his nudge to higher education as a means of empowerment. Saro
Gattu, for her magical ability to instill in me the greatest gift of all—a love for learning. …

[PDF][PDF] Serum Amyloid A is a Retinol Binding Protein that Transports Retinol during Bacterial Infection

CM Zlatkov - 2014 - utswmed-ir.tdl.org
… also like to thank Sureka, who as a newer student in the Hooper lab has bravely jumped
into my world of retinol biology and lent a helping hand with some experiments. I have to thank …

Toward cleaner air for a billion Indians

JS Apte, P Pant - Proceedings of the National Academy of …, 2019 - National Acad Sciences
Exposure to fine particulate matter (PM2. 5) is a major risk factor for premature death (1).
Few regions of the world experience ambient PM2. 5 concentrations as high as the Indo-…

Sex differences in brain metabolic activity: Beyond the concept of brain age

E Biskup, FC Quevenco, MT Ferretti… - Proceedings of the …, 2019 - National Acad Sciences
The main findings of the paper (1),“the female brain has a persistently lower metabolic brain
age—relative to their chronological age—compared with the male brain,” lend themselves …

Indian annual ambient air quality standard is achievable by completely mitigating emissions from household sources

S Chowdhury, S Dey, S Guttikunda… - Proceedings of the …, 2019 - National Acad Sciences
Exposures to ambient and household fine-particulate matter (PM 2.5 ) together are among
the largest single causes of premature mortality in India according to the Global Burden of …