User profiles for Susan D. Hester

Susan Hester

Assistant Research Scientist, University of Arizona
Verified email at email.arizona.edu
Cited by 452

[HTML][HTML] A multi-cell, multi-scale model of vertebrate segmentation and somite formation

SD Hester, JM Belmonte, JS Gens… - PLoS computational …, 2011 - journals.plos.org
Somitogenesis, the formation of the body's primary segmental structure common to all vertebrate
development, requires coordination between biological mechanisms at several scales. …

Toxicity profiles in mice treated with hepatotumorigenic and non-hepatotumorigenic triazole conazole fungicides: propiconazole, triadimefon, and myclobutanil

…, DC Wolf, MH George, SD Hester… - Toxicologic …, 2006 - journals.sagepub.com
Conazoles comprise a class of fungicides used in agriculture and as pharmaceutical products.
The fungicidal properties of conazoles are due to their inhibition of ergosterol biosynthesis…

Toxicity profiles in rats treated with tumorigenic and nontumorigenic triazole conazole fungicides: propiconazole, triadimefon, and myclobutanil

…, JW Allen, MH George, SD Hester… - Toxicologic …, 2006 - journals.sagepub.com
Conazoles are a class of azole based fungicides used in agriculture and as pharmaceutical
products. They have a common mode of antifungal action through inhibition of ergosterol …

Transcriptional profiles in liver from mice treated with hepatotumorigenic and nonhepatotumorigenic triazole conazole fungicides: propiconazole, triadimefon, and …

WO Ward, DA Delker, SD Hester, SF Thai… - Toxicologic …, 2006 - journals.sagepub.com
Conazoles are environmental and pharmaceutical fungicides. The present study relates the
toxicological effects of conazoles to alterations of gene and pathway transcription and …

Authentic Inquiry through Modeling in Biology (AIM-Bio): An introductory laboratory curriculum that increases undergraduates' scientific agency and skills

SD Hester, M Nadler, J Katcher, LK Elfring… - CBE—Life Sciences …, 2018 - Am Soc Cell Biol
Providing opportunities for science, technology, engineering, and mathematics undergraduates
to engage in authentic scientific practices is likely to influence their view of science and …

Quantitation of intracellular NAD (P) H can monitor an imbalance of DNA single strand break repair in base excision repair deficient cells in real time

J Nakamura, S Asakura, SD Hester… - Nucleic acids …, 2003 - academic.oup.com
DNA single strand breaks (SSBs) are one of the most frequent DNA lesions in genomic DNA
generated either by oxidative stress or during the base excision repair pathways. Here we …

Concordance of transcriptional and apical benchmark dose levels for conazole-induced liver effects in mice

VS Bhat, SD Hester, S Nesnow… - toxicological …, 2013 - academic.oup.com
The ability to anchor chemical class–based gene expression changes to phenotypic lesions
and to describe these changes as a function of dose and time informs mode-of-action …

Multicell simulations of development and disease using the CompuCell3D simulation environment

MH Swat, SD Hester, AI Balter, RW Heiland, BL Zaitlen… - Systems Biology, 2009 - Springer
Mathematical modeling and computer simulation have become crucial to biological fields
from genomics to ecology. However, multicell, tissue-level simulations of development and …

Transcriptional profiles in liver from rats treated with tumorigenic and non-tumorigenic triazole conazole fungicides: propiconazole, triadimefon, and myclobutanil

SD Hester, DC Wolf, S Nesnow… - Toxicologic …, 2006 - journals.sagepub.com
Conazoles are a class of fungicides used as pharmaceutical and agricultural agents. In
chronic bioassays in rats, triadimefon was hepatotoxic and induced follicular cell adenomas in …

Discrimination of tumorigenic triazole conazoles from phenobarbital by transcriptional analyses of mouse liver gene expression

…, W Ward, T Moore, H Ren, SD Hester - Toxicological …, 2009 - academic.oup.com
Conazoles are fungicides used to control fungal growth in environmental settings and to treat
humans with fungal infections. Mouse hepatotumorigenic conazoles display many of the …