[HTML][HTML] PD-L1 on host cells is essential for PD-L1 blockade–mediated tumor regression

…, A Mulgaonkar, X Liu, SM Harrington… - The Journal of …, 2018 - Am Soc Clin Investig
Programmed death–ligand 1 (PD-L1) expression on tumor cells is essential for T cell impairment,
and PD-L1 blockade therapy has shown unprecedented durable responses in several …

PD-1 restrains radiotherapy-induced abscopal effect

SS Park, H Dong, X Liu, SM Harrington, CJ Krco… - Cancer immunology …, 2015 - AACR
We investigated the influence of PD-1 expression on the systemic antitumor response (abscopal
effect) induced by stereotactic ablative radiotherapy (SABR) in preclinical melanoma …

Pathogenesis of enteroaggregative Escherichia coli infection

SM Harrington, EG Dudley… - FEMS microbiology …, 2006 - academic.oup.com
Enteroaggregative Escherichia coli (EAEC) is emerging as a significant diarrheal pathogen
in multiple population groups. Although most commonly associated with pediatric diarrhea in …

[HTML][HTML] B7-H1 expression in malignant pleural mesothelioma is associated with sarcomatoid histology and poor prognosis

…, T Peikert, YM Sheinin, SM Harrington… - Journal of thoracic …, 2014 - Elsevier
Introduction: B7 homolog 1 (B7-H1; aka programmed cell death 1 ligand 1) is a negative
costimulatory molecule that is associated with poor prognosis in many tumor types. Given the …

Tumor B7-H1 and B7-H3 expression in squamous cell carcinoma of the lung

JM Boland, ED Kwon, SM Harrington, JA Wampfler… - Clinical lung cancer, 2013 - Elsevier
Background Pulmonary squamous cell carcinoma has a poor prognosis, and new therapeutic
targets are needed. The aberrant expression of the immunomodulatory proteins B7-H1 …

Survival of patients with pulmonary tuberculosis: clinical and molecular epidemiologic factors

…, RD Moore, WR Bishai, SM Harrington… - Clinical infectious …, 2002 - academic.oup.com
Using restriction fragment–length polymorphism data, we conducted a retrospective cohort
study of 139 adult patients with pulmonary tuberculosis to investigate the clinical impact of …

The Pic Protease of Enteroaggregative Escherichia coli Promotes Intestinal Colonization and Growth in the Presence of Mucin

SM Harrington, J Sheikh, IR Henderson… - Infection and …, 2009 - Am Soc Microbiol
Enteroaggregative Escherichia coli (EAEC) is increasingly being recognized as a cause of
diarrheal disease in diverse populations. No small animal model is currently available to …

Soluble B7-H1: differences in production between dendritic cells and T cells

X Frigola, BA Inman, CJ Krco, X Liu, SM Harrington… - Immunology letters, 2012 - Elsevier
Tumor cells aberrantly express several T cell inhibitory molecules including members of the
B7-H co-regulatory family. Presumably tumor-expressed B7-H1 and B7-H3 confer resistance …

Detection of a molecular biomarker for zygomycetes by quantitative PCR assays of plasma, bronchoalveolar lavage, and lung tissue in a rabbit model of experimental …

M Kasai, SM Harrington, A Francesconi… - Journal of clinical …, 2008 - Am Soc Microbiol
We developed two real-time quantitative PCR (qPCR) assays, targeting the 28S rRNA gene,
for the diagnosis of zygomycosis caused by the most common, clinically significant …

Aggregative adherence fimbriae contribute to the inflammatory response of epithelial cells infected with enteroaggregative Escherichia coli

SM Harrington, MC Strauman, CM Abe… - Cellular …, 2005 - Wiley Online Library
Enteroaggregative Escherichia coli (EAEC) causes watery diarrhoea that is often mildly
inflammatory. Previous studies have reported that the flagellin of EAEC induces IL‐8 from …