User profiles for Susana Direito
Susana DireitoUniversity of Edinburgh Verified email at ed.ac.uk Cited by 922 |
Habitability: a review
Habitability is a widely used word in the geoscience, planetary science, and astrobiology
literature, but what does it mean? In this review on habitability, we define it as the ability of an …
literature, but what does it mean? In this review on habitability, we define it as the ability of an …
The significance of microbe-mineral-biomarker interactions in the detection of life on Mars and beyond
The detection of biomarkers plays a central role in our effort to establish whether there is, or
was, life beyond Earth. In this review, we address the importance of considering mineralogy …
was, life beyond Earth. In this review, we address the importance of considering mineralogy …
Sensitive life detection strategies for low-biomass environments: optimizing extraction of nucleic acids adsorbing to terrestrial and Mars analogue minerals
SOL Direito, A Marees… - FEMS microbiology …, 2012 - academic.oup.com
The adsorption of nucleic acids to mineral matrixes can result in low extraction yields and
negatively influences molecular microbial ecology studies, in particular for low-biomass …
negatively influences molecular microbial ecology studies, in particular for low-biomass …
[HTML][HTML] Soft matter science and the COVID-19 pandemic
Much of the science underpinning the global response to the COVID-19 pandemic lies in
the soft matter domain. Coronaviruses are composite particles with a core of nucleic acids …
the soft matter domain. Coronaviruses are composite particles with a core of nucleic acids …
Predictable properties of fitness landscapes induced by adaptational tradeoffs
Fitness effects of mutations depend on environmental parameters. For example, mutations
that increase fitness of bacteria at high antibiotic concentration often decrease fitness in the …
that increase fitness of bacteria at high antibiotic concentration often decrease fitness in the …
A roadblock-and-kill mechanism of action model for the DNA-targeting antibiotic ciprofloxacin
Fluoroquinolones, antibiotics that cause DNA damage by inhibiting DNA topoisomerases,
are clinically important, but their mechanism of action is not yet fully understood. In particular, …
are clinically important, but their mechanism of action is not yet fully understood. In particular, …
A wide variety of putative extremophiles and large beta-diversity at the Mars Desert Research Station (Utah)
Humankind's innate curiosity makes us wonder whether life is or was present on other
planetary bodies such as Mars. The EuroGeoMars 2009 campaign was organized at the Mars …
planetary bodies such as Mars. The EuroGeoMars 2009 campaign was organized at the Mars …
Systematic evaluation of bias in microbial community profiles induced by whole genome amplification
SOL Direito, E Zaura, M Little… - Environmental …, 2014 - Wiley Online Library
Whole genome amplification methods facilitate the detection and characterization of microbial
communities in low biomass environments. We examined the extent to which the actual …
communities in low biomass environments. We examined the extent to which the actual …
Planetary science and exploration in the deep subsurface: results from the MINAR Program, Boulby Mine, UK
…, DC Cullen, MT Downs, SOL Direito… - International Journal of …, 2017 - cambridge.org
The subsurface exploration of other planetary bodies can be used to unravel their geological
history and assess their habitability. On Mars in particular, present-day habitable conditions …
history and assess their habitability. On Mars in particular, present-day habitable conditions …
Computational design of probes to detect bacterial genomes by multivalent binding
Rapid methods for diagnosis of bacterial infections are urgently needed to reduce inappropriate
use of antibiotics, which contributes to antimicrobial resistance. In many rapid diagnostic …
use of antibiotics, which contributes to antimicrobial resistance. In many rapid diagnostic …