Live imaging of heart tube development in mouse reveals alternating phases of cardiac differentiation and morphogenesis

K Ivanovitch, S Temiño, M Torres - Elife, 2017 - elifesciences.org
10.7554/eLife.30668.001 During vertebrate heart development, two progenitor populations,
first and second heart fields (FHF, SHF), sequentially contribute to longitudinal subdivisions …

Clonal analysis identifies hemogenic endothelium as the source of the blood-endothelial common lineage in the mouse embryo

L Padrón-Barthe, S Temiño… - Blood, The Journal …, 2014 - ashpublications.org
The first blood and endothelial cells of amniote embryos appear in close association in the
blood islands of the yolk sac (YS). This association and in vitro lineage analyses have …

[PDF][PDF] A second heart field-derived vasculogenic niche contributes to cardiac lymphatics

G Lioux, X Liu, S Temiño, M Oxendine, E Ayala… - Developmental cell, 2020 - cell.com
The mammalian heart contains multiple cell types that appear progressively during embryonic
development. Advance in determining cardiac lineage diversification has often been …

[HTML][HTML] Control of mouse limb initiation and antero-posterior patterning by Meis transcription factors

I Delgado, G Giovinazzo, S Temiño, Y Gauthier… - Nature …, 2021 - nature.com
Meis1 and Meis2 are homeodomain transcription factors that regulate organogenesis through
cooperation with Hox proteins. Elimination of Meis genes after limb induction has shown …

[HTML][HTML] Pseudodynamic analysis of heart tube formation in the mouse reveals strong regional variability and early left–right asymmetry

…, A Desgrange, M Raiola, S Temiño… - Nature Cardiovascular …, 2022 - nature.com
Understanding organ morphogenesis requires a precise geometrical description of the
tissues involved in the process. The high morphological variability in mammalian embryos …

Cre recombinase microinjection for single-cell tracing and localised gene targeting

M Sendra, J de Dios Hourcade, S Temiño… - …, 2023 - journals.biologists.com
Tracing and manipulating cells in embryos are essential to understand development. Lipophilic
dye microinjections, viral transfection and iontophoresis have been key to map the origin …

Control of coronary lymphangiogenesis by epicardial VEGFC/D

E de la Cruz, V Cadenas, S Temiño, G Oliver, M Torres - bioRxiv, 2023 - biorxiv.org
The contractile ability of the mammalian heart critically relies on blood coronary circulation,
essential to provide oxygen and nutrients to myocardial cells. In addition, the lymphatic …

Epigenetic priming of embryonic lineages in the mammalian epiblast

…, J de Dios-Hourcade, S Temino Valbuena… - bioRxiv, 2024 - biorxiv.org
Understanding the diversification of mammalian cell lineages is an essential to embryonic
development, organ regeneration and tissue engineering. Shortly after implantation in the …

[PDF][PDF] Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression

MJ Bueno, IP de Castro, MG de Cedron, J Santos… - Cancer cell, 2008 - cell.com
… We thank Susana Temino for excellent technical assistance, M. Guerrero for CGH
analysis, and Amaia Lujambio for help with expression assays. We also thank I. …

[HTML][HTML] Forensic archaeometry applied to antiquities trafficking: the beginnings of an investigation at the frontiers of knowledge

I Rodríguez Temiño, A Yáñez, SE Jorge-Villar… - Arts, 2018 - mdpi.com
For most of its history, archaeology has too often taken an indulgent attitude toward looting
and antiquities trafficking. The primary response to these dangers has been to publish the …