User profiles for Susannah Hallal
 | Susannah HallalChris O'Brien Lifehouse Verified email at lh.org.au Cited by 709 |
[HTML][HTML] Deep sequencing of circulating exosomal microRNA allows non-invasive glioblastoma diagnosis
Exosomes are nano-sized extracellular vesicles released by many cells that contain
molecules characteristic of their cell of origin, including microRNA. Exosomes released by …
molecules characteristic of their cell of origin, including microRNA. Exosomes released by …
[HTML][HTML] A comprehensive proteomic SWATH-MS workflow for profiling blood extracellular vesicles: a new avenue for glioma tumour surveillance
Improving outcomes for diffuse glioma patients requires methods that can accurately and
sensitively monitor tumour activity and treatment response. Extracellular vesicles (EV) are …
sensitively monitor tumour activity and treatment response. Extracellular vesicles (EV) are …
[HTML][HTML] Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease
DM Mallawaaratchy, S Hallal, B Russell, L Ly… - Journal of neuro …, 2017 - Springer
Extracellular vesicles (EVs) play key roles in glioblastoma (GBM) biology and represent
novel sources of biomarkers that are detectable in the peripheral circulation. Despite this …
novel sources of biomarkers that are detectable in the peripheral circulation. Despite this …
The emerging clinical potential of circulating extracellular vesicles for non-invasive glioma diagnosis and disease monitoring
S Hallal, S Ebrahimkhani, B Shivalingam… - Brain tumor …, 2019 - Springer
Diffuse gliomas (grades II–IV) are amongst the most frequent and devastating primary brain
tumours of adults. Currently, patients are monitored by clinical examination and radiographic …
tumours of adults. Currently, patients are monitored by clinical examination and radiographic …
Extracellular vesicles from neurosurgical aspirates identifies chaperonin containing TCP1 subunit 6A as a potential glioblastoma biomarker with prognostic …
Glioblastoma, WHO‐grade IV glioma, carries a dismal prognosis owing to its infiltrative
growth and limited treatment options. Glioblastoma‐derived extracellular vesicles (EVs; 30–1000 …
growth and limited treatment options. Glioblastoma‐derived extracellular vesicles (EVs; 30–1000 …
Understanding the extracellular vesicle surface for clinical molecular biology
Extracellular vesicles (EVs) are lipid‐membrane enclosed nanoparticles that play significant
roles in health and disease. EVs are abundant in body fluids and carry an array of …
roles in health and disease. EVs are abundant in body fluids and carry an array of …
Extensive surface protein profiles of extracellular vesicles from cancer cells may provide diagnostic signatures from blood samples
L Belov, KJ Matic, S Hallal, OG Best… - Journal of …, 2016 - Taylor & Francis
Extracellular vesicles (EV) are membranous particles (30–1,000 nm in diameter) secreted by
cells. Important biological functions have been attributed to 2 subsets of EV, the exosomes (…
cells. Important biological functions have been attributed to 2 subsets of EV, the exosomes (…
[HTML][HTML] Glioblastoma biomarkers in urinary extracellular vesicles reveal the potential for a 'liquid gold'biopsy
Background Biomarkers that reflect glioblastoma tumour activity and treatment response are
urgently needed to help guide clinical management, particularly for recurrent disease. As …
urgently needed to help guide clinical management, particularly for recurrent disease. As …
[HTML][HTML] Deep sequencing of small RNAs from neurosurgical extracellular vesicles substantiates miR-486-3p as a circulating biomarker that distinguishes …
S Hallal, S Ebrahim Khani, H Wei, MYT Lee… - International journal of …, 2020 - mdpi.com
Extracellular vesicles (EVs) play key roles in glioblastoma (GBM; astrocytoma grade IV) biology
and are novel sources of biomarkers. EVs released from GBM tumors can cross the blood…
and are novel sources of biomarkers. EVs released from GBM tumors can cross the blood…
[HTML][HTML] Understanding the epitranscriptome for avant-garde brain tumour diagnostics
Simple Summary Glioblastoma is a complex and aggressive primary brain tumour that is
rapidly fatal. Timely and accurate diagnosis is therefore crucial. Here, we explore the newly …
rapidly fatal. Timely and accurate diagnosis is therefore crucial. Here, we explore the newly …