User profiles for Susma Ghimire

Sushma Ghimire

Georgia State University
Verified email at gatech.edu
Cited by 1

[PDF][PDF] A critical role of hepatic GABA in the metabolic dysfunction and hyperphagia of obesity

CE Geisler, S Ghimire, SM Bruggink, KE Miller… - Cell reports, 2021 - cell.com
Hepatic lipid accumulation is a hallmark of type II diabetes (T2D) associated with hyperinsulinemia,
insulin resistance, and hyperphagia. Hepatic synthesis of GABA, catalyzed by GABA-…

Role of ketone signaling in the hepatic response to fasting

CE Geisler, S Ghimire, RL Bogan… - American Journal of …, 2019 - journals.physiology.org
Ketosis is a metabolic adaptation to fasting, nonalcoholic fatty liver disease (NAFLD), and
prolonged exercise. β-OH butyrate acts as a transcriptional regulator and at G protein-coupled …

[PDF][PDF] Hepatocyte membrane potential regulates serum insulin and insulin sensitivity by altering hepatic GABA release

CE Geisler, S Ghimire, C Hepler, KE Miller… - Cell reports, 2021 - cell.com
Hepatic lipid accumulation in obesity correlates with the severity of hyperinsulinemia and
systemic insulin resistance. Obesity-induced hepatocellular lipid accumulation results in …

[HTML][HTML] The role of GPR109a signaling in niacin induced effects on fed and fasted hepatic metabolism

CE Geisler, KE Miller, S Ghimire… - International Journal of …, 2021 - mdpi.com
Signaling through GPR109a, the putative receptor for the endogenous ligand β-OH butyrate,
inhibits adipose tissue lipolysis. Niacin, an anti-atherosclerotic drug that can induce insulin …

Analysis of Fault location methods on transmission lines

S Ghimire - 2014 - scholarworks.uno.edu
Abstract Analysis of different types of fault is an important and complex task in a power system.
Accurate fault analysis requires models that determine fault distances in a transmission …

[HTML][HTML] Fitness trade-offs and developmental constraints in the evolution of soma: an experimental study in a volvocine alga

MD Herron, S Ghimire, CR Vinikoor… - Evolutionary ecology …, 2014 - ncbi.nlm.nih.gov
Background: The evolution of mortal somatic cells was a critical step in the evolution of
complex body plans and the major radiations of multicellular life. In the volvocine green algae, …

A stable EEG epilepsy network spans from infraslow to ripple and from interictal to ictus

S Ghimire, M Dhamala, CM Epstein - Journal of Clinical …, 2024 - journals.lww.com
Purpose: To characterize the epilepsy network as reflected in intracranial electroencephalography
(iEEG) across the full spectrum of iEEG frequencies and different phases of epilepsy, …

TMEM135 is an LXR-inducible regulator of peroxisomal metabolism

…, TW Madanayake, JD Hennebold, S Ghimire… - BioRxiv, 2018 - biorxiv.org
The liver x receptors (LXRs) are key regulators of systemic lipid metabolism. We determined
whether transmembrane protein 135 (TMEM135) is an LXR target gene and its physiologic …

Exploring warming up activities used by secondary level English teachers in Kawaswoti Municipality

S Ghimire - 2023 - elibrary.tucl.edu.np
This is a research entitled Exploring warming up activities used by secondary level English
teacher in Nawalparasi district (East). The main objective of the study was to explore the …

Identifying a Mechanism by Which Hepatic Steatosis Drives Hypertension Development

S Bruggink, S Ghimire - Obesity, 2021 - search.proquest.com
Background: Hepatic steatosis affects 1 in 4 people worldwide and is associated with an
increased risk for the development of hypertension. Even in patients without hypertension, the …