Sequence signatures and mRNA concentration can explain two‐thirds of protein abundance variation in a human cell line
…, D Ko, SY Le, BA Shapiro, SC Burns… - Molecular systems …, 2010 - embopress.org
Transcription, mRNA decay, translation and protein degradation are essential processes during
eukaryotic gene expression, but their relative global contributions to steady‐state protein …
eukaryotic gene expression, but their relative global contributions to steady‐state protein …
Site identification in high-throughput RNA–protein interaction data
PJ Uren, E Bahrami-Samani, SC Burns, M Qiao… - …, 2012 - academic.oup.com
Motivation: Post-transcriptional and co-transcriptional regulation is a crucial link between
genotype and phenotype. The central players are the RNA-binding proteins, and experimental …
genotype and phenotype. The central players are the RNA-binding proteins, and experimental …
[HTML][HTML] Before it gets started: regulating translation at the 5′ UTR
…, AD Smith, M Qiao, U Suresh, SC Burns… - International Journal of …, 2012 - hindawi.com
Translation regulation plays important roles in both normal physiological conditions and
diseases states. This regulation requires cis-regulatory elements located mostly in 5′ and 3′ …
diseases states. This regulation requires cis-regulatory elements located mostly in 5′ and 3′ …
[HTML][HTML] Functional genomics analyses of RNA-binding proteins reveal the splicing regulator SNRPB as an oncogenic candidate in glioblastoma
BR Correa, PR de Araujo, M Qiao, SC Burns, C Chen… - Genome Biology, 2016 - Springer
Background Glioblastoma (GBM) is the most common and aggressive type of brain tumor.
Currently, GBM has an extremely poor outcome and there is no effective treatment. In this …
Currently, GBM has an extremely poor outcome and there is no effective treatment. In this …
[HTML][HTML] Genomic analyses of musashi1 downstream targets show a strong association with cancer-related processes
…, PC Sanchez-Diaz, C Vogel, SC Burns… - Journal of biological …, 2009 - ASBMB
Musashi1 (Msi1) is a highly conserved RNA-binding protein with pivotal functions in stem
cell maintenance, nervous system development, and tumorigenesis. Despite its importance, …
cell maintenance, nervous system development, and tumorigenesis. Despite its importance, …
[PDF][PDF] IGF2BP3 modulates the interaction of invasion-associated transcripts with RISC
…, JM Draper, A Wallace, O Cazarez, SC Burns… - Cell reports, 2016 - cell.com
Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) expression correlates with
malignancy, but its role(s) in pathogenesis remains enigmatic. We interrogated the IGF2BP3-…
malignancy, but its role(s) in pathogenesis remains enigmatic. We interrogated the IGF2BP3-…
[HTML][HTML] The RNA-binding protein Musashi1 affects medulloblastoma growth via a network of cancer-related genes and is an indicator of poor prognosis
…, JA Gelfond, R de Sousa Abreu, SC Burns… - The American journal of …, 2012 - Elsevier
Musashi1 (Msi1) is a highly conserved RNA-binding protein that is required during the
development of the nervous system. Msi1 has been characterized as a stem cell marker, …
development of the nervous system. Msi1 has been characterized as a stem cell marker, …
The oncogenic RNA-binding protein Musashi1 is regulated by tumor suppressor miRNAs
Musashi1 (Msi1) is an evolutionarily conserved RNA-binding protein that has been implicated
in processes like stem cell fate, nervous system development, and tumorigenesis via its …
in processes like stem cell fate, nervous system development, and tumorigenesis via its …
[HTML][HTML] Genomic analyses of the RNA-binding protein Hu antigen R (HuR) identify a complex network of target genes and novel characteristics of its binding sites
The ubiquitously expressed RNA-binding protein Hu antigen R (HuR) or ELAVL1 is implicated
in a variety of biological processes as well as being linked with a number of diseases, …
in a variety of biological processes as well as being linked with a number of diseases, …
RNA-binding protein Musashi1 is a central regulator of adhesion pathways in glioblastoma
…, PR de Araujo, R Pötschke, SC Burns… - … and cellular biology, 2015 - Taylor & Francis
The conserved RNA-binding protein Musashi1 (MSI1) has emerged as a key oncogenic factor
in numerous solid tumors, including glioblastoma. However, its mechanism of action has …
in numerous solid tumors, including glioblastoma. However, its mechanism of action has …