Nucleosomes cover most of the genome and are thought to be displaced by transcription
factors in regions that direct gene expression. However, the modes of interaction between …

‘Pioneer’ transcription factors are required for stem-cell pluripotency, cell differentiation and
cell reprogramming 1 , 2 . Pioneer factors can bind nucleosomal DNA to enable gene …

10.7554/eLife.32493.001 COPI-coated vesicles mediate trafficking within the Golgi apparatus
and from the Golgi to the endoplasmic reticulum. The structures of membrane protein coats…

10.7554/eLife.26691.001 COPI coated vesicles mediate trafficking within the Golgi apparatus
and between the Golgi and the endoplasmic reticulum. Assembly of a COPI coated vesicle …

Clathrin-mediated endocytosis, the main trafficking route from the plasma membrane to the
cytoplasm, is critical to many fundamental cellular processes. Clathrin, coupled to the …

Retroviruses evolved from long terminal repeat (LTR) retrotransposons by acquisition of
envelope functions, and subsequently reinvaded host genomes. Together, endogenous …

Throughout the genome, nucleosomes often form regular arrays that differ in nucleosome
repeat length (NRL), occupancy of linker histone H1 and transcriptional activity. Here, we …

In the ongoing search for practical uses of rare-earth metal nanoparticles, cerium dioxide
nanoparticles (nanoceria) have received special attention. The purpose of this research was to …

Cytoplasmic streaming in plant cells is an effective means of intracellular transport. The cycling
of ions and metabolites between the cytosol and chloroplasts in illuminated cell regions …

Cytoplasmic streaming in Characean internodes enables rapid intracellular transport and
facilitates interactions between spatially remote cell regions. Cyclosis-mediated distant …