Hemoglobin (Hb)-based oxygen carriers (HBOCs) have been engineered to replace or
augment the oxygen carrying capacity of erythrocytes. However, clinical results have generally …

Hemoglobin (Hb)-based oxygen carriers (HBOC) are modified extracellular proteins, designed
to replace or augment the oxygen-carrying capacity of erythrocytes. However, clinical …

In order to infuse hemoglobin into the vasculature as an oxygen therapeutic or blood substitute,
it is necessary to increase the size of the molecule to enhance vascular retention. This …

Purpose: There is compelling evidence of a relationship between poly(ADP-ribosyl)ation
and tumorigenesis; however, much less is known about the role of specific targets of poly(ADP-…

We previously reported the association of elevated levels of the multifunctional transcription
factor, CCCTC binding factor (CTCF), in breast cancer cells with the specific anti-apoptotic …

Background Nucleosome repositioning in cancer is believed to cause many changes in
genome organisation and gene expression. Understanding these changes is important to …

CTCF is an evolutionarily conserved and ubiquitously expressed architectural protein regulating
a plethora of cellular functions via different molecular mechanisms. CTCF can undergo …

X-ray micro-CT has been used to study the tracheal system of Pre and Post hibernation
Queen wasps (Vespula vulgaris) and their workers. We have compared our findings in wasps …

Chromatin immunoprecipitation (ChIP) is an important technique in the study of DNA/protein
interactions. The ChIP procedure, however, has limitations in that it is lengthy, can be …

Stages of the moult cycle of the amphipod Gammarus pulex have been previously characterised
based on the examination of either apolysis of the 3 rd dactyl, or the whole body and …