User profiles for Sweelin Chew
Sweelin ChewPostdoctoral researcher, University of Eastern Finland Verified email at uef.fi Cited by 200 |
[HTML][HTML] Impairment of mitochondrial function by particulate matter: Implications for the brain
Research efforts in the past decades have provided insight into the adverse health effects of
air pollution exposure. Exposure to airborne particulate matter is known to impair the …
air pollution exposure. Exposure to airborne particulate matter is known to impair the …
[HTML][HTML] Neuron-astrocyte transmitophagy is altered in Alzheimer's disease
Under physiological conditions in vivo astrocytes internalize and degrade neuronal
mitochondria in a process called transmitophagy. Mitophagy is widely reported to be impaired in …
mitochondria in a process called transmitophagy. Mitophagy is widely reported to be impaired in …
[HTML][HTML] Single-cell RNA-Seq analysis of olfactory mucosal cells of Alzheimer's disease patients
Olfaction is orchestrated by olfactory mucosal cells located in the upper nasal cavity. Olfactory
dysfunction manifests early in several neurodegenerative disorders including Alzheimer’s …
dysfunction manifests early in several neurodegenerative disorders including Alzheimer’s …
[HTML][HTML] Human-derived air–liquid interface cultures decipher Alzheimer's disease–SARS-CoV-2 crosstalk in the olfactory mucosa
Background The neurological effects of the coronavirus disease of 2019 (COVID-19) raise
concerns about potential long-term consequences, such as an increased risk of Alzheimer's …
concerns about potential long-term consequences, such as an increased risk of Alzheimer's …
[HTML][HTML] Urban air particulate matter induces mitochondrial dysfunction in human olfactory mucosal cells
S Chew, R Lampinen, L Saveleva, P Korhonen… - Particle and Fibre …, 2020 - Springer
Background The adverse effects of air pollutants including particulate matter (PM) on the
central nervous system is increasingly reported by epidemiological, animal and post-mortem …
central nervous system is increasingly reported by epidemiological, animal and post-mortem …
[HTML][HTML] Upregulation of Integrin beta-3 in astrocytes upon Alzheimer's disease progression in the 5xFAD mouse model
…, N Thind, C Andrès, R Lampinen, S Chew… - Neurobiology of …, 2024 - Elsevier
Integrins are receptors that have been linked to various brain disorders, including Alzheimer's
disease (AD), the most prevalent neurodegenerative disorder. While Integrin beta-3 (ITGB3…
disease (AD), the most prevalent neurodegenerative disorder. While Integrin beta-3 (ITGB3…
[HTML][HTML] Emissions from modern engines induce distinct effects in human olfactory mucosa cells, depending on fuel and aftertreatment
Ultrafine particles (UFP) with a diameter of ≤0.1 μm, are contributors to ambient air
pollution and derived mainly from traffic emissions, yet their health effects remain poorly …
pollution and derived mainly from traffic emissions, yet their health effects remain poorly …
[HTML][HTML] Subacute inhalation of ultrafine particulate matter triggers inflammation without altering amyloid beta load in 5xFAD mice
Epidemiological studies reveal that air pollution exposure may exacerbate neurodegeneration.
Ultrafine particles (UFPs) are pollutants that remain unregulated in ambient air by …
Ultrafine particles (UFPs) are pollutants that remain unregulated in ambient air by …
[HTML][HTML] The interaction between circulating cell-free mitochondrial DNA and inflammatory cytokines in predicting human mental health issue risk in adolescents: an …
A Alatalo, I de Sousa Maciel, N Kucháriková, S Chew… - Biomedicines, 2023 - mdpi.com
Adolescence is often a challenging time in which psychiatric issues have a strong connection
to mental health disorders later in life. The early identification of the problems can reduce …
to mental health disorders later in life. The early identification of the problems can reduce …
[HTML][HTML] TUBE project: Transport-derived ultrafines and the brain effects
The adverse effects of air pollutants on the respiratory and cardiovascular systems are
unquestionable. However, in recent years, indications of effects beyond these organ systems …
unquestionable. However, in recent years, indications of effects beyond these organ systems …