Purpose Previously, over-expression of the long noncoding RNA (lncRNA) HOTAIR has
been found to be associated with the invasive and metastatic capacities of several epithelial …

In order to be effective models to identify biomarkers of chemotherapy response, cancer cell
lines require thorough characterization. In this study, we characterised the widely used high …

The Homeobox (HOX) genes encode important transcription factors showing deregulated
expression in several cancers. However, their role in cervical cancer pathogenesis, remains …

BRCA1/2 mutations and poly (ADP-ribose) polymerase (PARP) inhibitors are paradigmatic
of synthetic lethal therapy. However, the activity of PARP inhibitors seems to vary …

Head and neck cancer (HNC) differs at anatomical sites and hypopharyngeal cancer (HPC)
is a type of HNC. The non-surgical treatment option for advanced cases of HPC is …

Heterogeneity in cervical cancers (CaCx) in terms of HPV16 physical status prompted us to
investigate the mRNA and miRNA signatures among the different categories of CaCx …

Human papillomavirus type-16 (HPV16) is classified into lineages, A, B, C and D and 10 sub-lineages
portraying variable infectivity, persistence, and cytological outcomes, however, …

Simple Summary Several chemotherapy drugs are approved for ovarian cancer treatment in
the neo-adjuvant/adjuvant setting as well as following relapse. These include carboplatin, …

Non–T-cell–inflamed immunologically “cold” tumor microenvironments (TME) are associated
with poor responsiveness to immune checkpoint blockade (ICB) and can be sculpted by …

The human body is constantly exposed to a variety of oxidizing agents from naturally
occurring processes, environmental stimuli/pollutants, and through lifestyle-related stress/activities. …