Background Understanding podocyte-specific responses to injury at a systems level is
difficult because injury leads to podocyte loss or an increase of extracellular matrix, altering …

Background Inhibition of angiotensin II (AngII) signaling, a therapeutic mainstay of glomerular
kidney diseases, is thought to act primarily through regulating glomerular blood flow and …

Podocytes are highly specialized, epithelial, postmitotic cells, which maintain the renal
filtration barrier. When adapting to considerable metabolic and mechanical stress, podocytes …

The cellular responses induced by mitochondrial dysfunction remain elusive. Intrigued by
the lack of almost any glomerular phenotype in patients with profound renal ischemia, we …

Mitochondrial dysfunction and alterations in energy metabolism have been implicated in a
variety of human diseases. Mitochondrial fusion is essential for maintenance of mitochondrial …

This Editorial precedes an upcoming series of research and review articles focused on the
field of podocyte physiology and pathophysiology for which a Call for Papers is being issued (…

The renal filtration barrier is maintained by the renal podocyte, an epithelial postmitotic cell.
Immortalized mouse podocyte cell lines—both in the differentiated and undifferentiated state…

Kidney filtration is ensured by the interaction of podocytes, endothelial and mesangial cells.
Immunoglobulin accumulation at the filtration barrier is pathognomonic for glomerular injury. …

Biological and biomedical research using Drosophila melanogaster as a model organism
has gained recognition through several Nobel prizes within the last 100 years. Drosophila …

… Author links open overlay panel Sybille Koehler 1 2 3 13 14 , Johanna Odenthal 1 2 13 ,
Vivian Ludwig 1 2 , David Unnersjö Jess 1 2 , Martin Höhne 1 2 4 , Christian Jüngst 4 , Ferdi …