Tumor-derived exosomes in the regulation of macrophage polarization
Background This review focuses on exosomes derived from various cancer cells. The
review discusses the possibility of differentiating macrophages in alternatively activated anti-…
review discusses the possibility of differentiating macrophages in alternatively activated anti-…
Potential therapeutic targets for inflammation in toll-like receptor 4 (TLR4)-mediated signaling pathways
Inflammation is set off when innate immune cells detect infection or tissue injury. Tight control
of the severity, duration, and location of inflammation is an absolute requirement for an …
of the severity, duration, and location of inflammation is an absolute requirement for an …
[HTML][HTML] Uncovering spatiotemporal heterogeneity of high-grade gliomas: From disease biology to therapeutic implications
Glioblastomas (GBM) are the most common and aggressive tumors of the central nervous
system. Rapid tumor growth and diffuse infiltration into healthy brain tissue, along with high …
system. Rapid tumor growth and diffuse infiltration into healthy brain tissue, along with high …
[HTML][HTML] Facile fabrication of highly efficient modified ZnO photocatalyst with enhanced photocatalytic, antibacterial and anticancer activity
The degradation of organic pollutants in the aqueous medium using semiconductor
photocatalysts has become an attractive method for detoxification of water. ZnO is an efficient …
photocatalysts has become an attractive method for detoxification of water. ZnO is an efficient …
[HTML][HTML] Spatiotemporal analysis of glioma heterogeneity reveals COL1A1 as an actionable target to disrupt tumor progression
Intra-tumoral heterogeneity is a hallmark of glioblastoma that challenges treatment efficacy.
However, the mechanisms that set up tumor heterogeneity and tumor cell migration remain …
However, the mechanisms that set up tumor heterogeneity and tumor cell migration remain …
Evaluation of protective immunity of Leptospira immunoglobulin like protein A (LigA) DNA vaccine against challenge in hamsters
SM Faisal, WW Yan, CS Chen, RUM Palaniappan… - Vaccine, 2008 - Elsevier
We demonstrated earlier that immunization with recombinant Leptospira immunoglobulin
like protein A (LigA) induced significant protection against virulent Leptospira interrogans …
like protein A (LigA) induced significant protection against virulent Leptospira interrogans …
[HTML][HTML] Current approaches for glioma gene therapy and virotherapy
Glioblastoma (GBM) is the most common and aggressive primary brain tumor in the adult
population and it carries a dismal prognosis. Inefficient drug delivery across the blood brain …
population and it carries a dismal prognosis. Inefficient drug delivery across the blood brain …
Resveratrol suppresses the proliferation of breast cancer cells by inhibiting fatty acid synthase signaling pathway
In breast cancer cells, overexpression of human epidermal growth factor receptor 2 (HER2)
increases the translation of fatty acid synthase (FASN) by altering the activity of PI3K/Akt …
increases the translation of fatty acid synthase (FASN) by altering the activity of PI3K/Akt …
[HTML][HTML] Immunogenicity and protective efficacy of recombinant Leptospira immunoglobulin-like protein B (rLigB) in a hamster challenge model
W Yan, SM Faisal, SP McDonough, TJ Divers… - Microbes and …, 2009 - Elsevier
… Author links open overlay panel Weiwei Yan a , Syed M. Faisal a , Sean P. McDonough a ,
… Development Corporation (BRDC), the Harry M. Zweig Memorial Fund for Equine Research, …
… Development Corporation (BRDC), the Harry M. Zweig Memorial Fund for Equine Research, …
[HTML][HTML] Mangiferin from Pueraria tuberosa reduces inflammation via inactivation of NLRP3 inflammasome
…, H Beeda, GH Philip, D Muralidhara Rao, SM Faisal - Scientific Reports, 2017 - nature.com
Recent reports have demonstrated the role of phyto-constituents in modulating inflammatory
responses. Mangiferin isolated from Mangifera indica is known to induce potent anti-…
responses. Mangiferin isolated from Mangifera indica is known to induce potent anti-…