Synaptic transmission in the brain generally depends on action potentials. However, recent
studies indicate that subthreshold variation in the presynaptic membrane potential also …

The extracellular signal‐regulated kinases (ERK) signalling cascade is a key pathway that
mediates the NMDA receptor (NMDAR)‐dependent neuronal plasticity and survival. However, …

Highlights • Several mechanisms control faithful action potential propagation along the axon.
• Action potential waveform is compartmentalized in different axonal segments. • Analog …

Extrasynaptic actions of glutamate are limited by high-affinity transporters expressed by
perisynaptic astroglial processes (PAPs): this helps maintain point-to-point transmission in …

The dynamics of inhibitory circuits in the cortex is thought to rely mainly on synaptic
modifications. We challenge this view by showing that hippocampal parvalbumin-positive basket …

The development of GABAergic synapses is associated with an excitatory to inhibitory shift
of the actions of GABA because of a reduction of [Cl − ] i . This is due to a delayed postnatal …

Action potentials (APs) in the mammalian brain are thought to represent the smallest unit of
information transmitted by neurons to their postsynaptic targets. According to this view, …

In the mammalian brain, synaptic transmission usually depends on presynaptic action
potentials (APs) in an all-or-none (or digital) manner. Recent studies suggest, however, that …

Homeostatic plasticity of intrinsic excitability goes hand in hand with homeostatic plasticity
of synaptic transmission. However, the mechanisms linking the two forms of homeostatic …

Calculations of entropy of a signal or mutual information between two variables are valuable
analytical tools in the field of neuroscience. They can be applied to all types of data, capture …