Amyloid-β (Aβ) drives the synaptic impairment and dendritic spine loss characteristic of
Alzheimer's disease (AD), but how Aβ affects the actin cytoskeleton remains unknown and …

The sequence of cellular dysfunctions in preclinical Alzheimer’s disease must be understood
if we are to plot new therapeutic routes. Hippocampal neuronal hyperactivity is one of the …

Fluorescent staining of astrocytes without damaging or interfering with normal brain functions
is essential for intravital microscopy studies. Current methods involved either transgenic …

Background Excessive synaptic loss is thought to be one of the earliest events in Alzheimer’s
disease (AD). However, the key mechanisms that maintain plasticity of synapses during …

Maurocalcine (MCa) is a 33-amino acid residue peptide toxin initially isolated from the scorpion
Scorpio maurus maurus. Its structural and functional features make it resembling many …

… Anthony Bosson and Sylvie Boisseau contributed equally to … Anthony Bosson and Sylvie
Boisseau contributed equally to … Anthony Bosson and Sylvie Boisseau contributed equally to …

In spermatozoa, voltage‐dependent calcium channels (VDCC) have been involved in different
cellular functions like acrosome reaction (AR) and sperm motility. Multiple types of VDCC …

Alterations of excitatory synaptic function are the strongest correlate to the pathologic
disturbance of cognitive ability observed in the early stages of Alzheimer's disease (AD). This …

Maurocalcine (MCa) is a 33-amino acid residue peptide that was initially identified in the
Tunisian scorpion Scorpio maurus palmatus. This peptide triggers interest for three main …

Store-operated channels (SOCs) are recruited in response to the release of Ca 2+ from
intracellular stores. They allow a voltage-independent entry of Ca 2+ into the cytoplasm also …