User profiles for T Harrop

Thomas WR Harrop

University of Melbourne
Verified email at unimelb.edu.au
Cited by 665

Fe (III) and Co (III) centers with carboxamido nitrogen and modified sulfur coordination: lessons learned from nitrile hydratase

TC Harrop, PK Mascharak - Accounts of chemical research, 2004 - ACS Publications
Nitrile hydratase (NHase) is a non-heme Fe(III) or non-corrinoid Co(III) metalloenzyme with
an unprecedented coordination sphere comprising deprotonated carboxamido nitrogens and …

Structural and spectroscopic models of the A-cluster of acetyl coenzyme a synthase/carbon monoxide dehydrogenase: Nature's Monsanto acetic acid catalyst

TC Harrop, PK Mascharak - Coordination Chemistry Reviews, 2005 - Elsevier
… When the Tl + salt of PhT t Bu t in CH 2 Cl 2 is mixed with a methanolic solution of [Ni(H 2
O) 6 ]Cl 2 , the red Ni(II) complex [( PhT t Bu t )Ni(Cl)] (8) is formed in good yield (Fig. 4) [47]. …

[PDF][PDF] Population genomics of the critically endangered kākāpō

…, G Formenti, O Fedrigo, J Guhlin, TWR Harrop… - Cell Genomics, 2021 - cell.com
… Finally, we estimated the split time (T), assuming no coalescent events since divergence
between the mainland and Stewart Island using the PSMC approach applied to a pseudo-…

Prevalence and associated harm of engagement in self-asphyxial behaviours ('choking game') in young people: a systematic review

H Busse, T Harrop, D Gunnell, R Kipping - Archives of disease in …, 2015 - adc.bmj.com
Objective To assess the prevalence of engagement in self-asphyxial (risk-taking) behaviour
(SAB) (‘choking game’) and associated morbidity and mortality in children and young people …

Reactions of synthetic [2Fe-2S] and [4Fe-4S] clusters with nitric oxide and nitrosothiols

TC Harrop, ZJ Tonzetich, E Reisner… - Journal of the American …, 2008 - ACS Publications
The interaction of nitric oxide (NO) with iron−sulfur cluster proteins results in degradation and
breakdown of the cluster to generate dinitrosyl iron complexes (DNICs). In some cases the …

A sensitive and selective fluorescence sensor for the detection of arsenic (III) in organic media

VC Ezeh, TC Harrop - Inorganic chemistry, 2012 - ACS Publications
Arsenic contamination is a leading environmental problem. As such, levels of this toxic
metalloid must be constantly monitored by reliable and low-cost methodologies. Because the …

[PDF][PDF] TCR-or cytokine-activated CD8+ mucosal-associated invariant T cells are rapid polyfunctional effectors that can coordinate immune responses

…, M Schneider, SM de la Harpe, TWR Harrop… - Cell reports, 2019 - cell.com
Mucosal-associated invariant T (MAIT) cells can be activated via either their T cell receptor (TCR),
which recognizes MR1-bound pyrimidines derived from microbial riboflavin …

Interaction of nitric oxide with tetrathiolato iron (II) complexes: relevance to the reaction pathways of iron nitrosyls in sulfur-rich biological coordination environments

TC Harrop, D Song, SJ Lippard - Journal of the American …, 2006 - ACS Publications
… of 1 with concomitant generation of the disulfide t BuSS t Bu. Passage of excess NO (g) …
DNIC 3 can also be readily achieved by addition of excess t BuS - to an MeCN solution of 2. …

[HTML][HTML] Creating and validating an algorithm to measure AIDS mortality in the adult population using verbal autopsy

…, JT Boerma, G Chawira, K Gaitskell, T Harrop… - PLoS …, 2006 - journals.plos.org
Background Vital registration and cause of death reporting is incomplete in the countries in
which the HIV epidemic is most severe. A reliable tool that is independent of HIV status is …

Using Drosophila melanogaster to validate metabolism-based insecticide resistance from insect pests

PJ Daborn, C Lumb, TWR Harrop, A Blasetti… - Insect biochemistry and …, 2012 - Elsevier
Identifying molecular mechanisms of insecticide resistance is important for preserving
insecticide efficacy, developing new insecticides and implementing insect control. The metabolic …