Several viruses infect the mammalian central nervous system (CNS), some with devastating
consequences, others resulting in chronic or persistent infections associated with little or no …

Most primary organic-particulate emissions are semivolatile; thus, they partially evaporate
with atmospheric dilution, creating substantial amounts of low-volatility gas-phase material. …

IFN-γ-inducible protein 10 (IP-10, CXCL10), a chemokine secreted from cells stimulated with
type I and II IFNs and LPS, is a chemoattractant for activated T cells. Expression of IP-10 is …

… Glass WG, Liu MT, Kuziel WA, Lane TE. Reduced macrophage infiltration and demyelination
in mice lacking the chemokine receptor CCR5 following infection with a neurotropic …

Rat ameboid microglia are able to lyse rat oligodendrocytes in vitro. The lysis is inhibited by
transforming growth factor-beta, antagonists of nitric oxide (NO) production, as well as …

Viral infection of the central nervous system (CNS) poses unique challenges to the immune
system with regards to controlling and eliminating the invading pathogen. These obstacles …

… Each lane represents an individual mouse. (B) The rate of epithelial cell turnover in IL-13
–/– mice, day 14. (C) Percentage of labeled cells recorded at each position (0 to 30), day 14 in …

Neutrophils are innate immune cells that counter pathogens by many mechanisms,
including release of antimicrobial proteins such as calprotectin to inhibit bacterial growth. …

The innate immune system is strongly implicated in the pathogenesis of Alzheimer’s disease
(AD). In contrast, the role of adaptive immunity in AD remains largely unknown. However, …

… LN cells from donor SJL mice immunized with PLP 139-151 in IFA were cultured with antigen
in the presence of either recombinant IL-23 (for the generation of Th17 cells), IL-12 (for the …