User profiles for T. L. Kinzer-Ursem

Tamara Kinzer-Ursem

Associate Professor of Biomedical Engineering, Associate Dean for Graduate and …
Verified email at purdue.edu
Cited by 1250

Physical characterization of nanoparticle size and surface modification using particle scattering diffusometry

…, JW Salameh, ST Wereley, TL Kinzer-Ursem - …, 2016 - pubs.aip.org
As the field of colloidal science continues to expand, tools for rapid and accurate physiochemical
characterization of colloidal particles will become increasingly important. Here, we …

[HTML][HTML] The dynamic relationship of breast cancer cells and fibroblasts in fibronectin accumulation at primary and metastatic tumor sites

…, H George, AM Saleh, A Abdullah, TL Kinzer-Ursem… - Cancers, 2020 - mdpi.com
In breast cancer (BC), tissue stiffening via fibronectin (FN) and collagen accumulation is
associated with advanced disease progression at both the primary tumor and metastatic sites. …

[HTML][HTML] Incorporation of non-canonical amino acids into the developing murine proteome

S Calve, AJ Witten, AR Ocken, TL Kinzer-Ursem - Scientific Reports, 2016 - nature.com
Abstract Analysis of the developing proteome has been complicated by a lack of tools that
can be easily employed to label and identify newly synthesized proteins within complex …

[HTML][HTML] Non-canonical amino acid labeling in proteomics and biotechnology

…, S Calve, BC Bundy, TL Kinzer-Ursem - Journal of Biological …, 2019 - Springer
… More recently, Calve and Kinzer-Ursem demonstrated that two days of intraperitoneal
injection of Aha and Hpg is sufficient for systemic incorporation of the Met analogs into the …

PD-LAMP smartphone detection of SARS-CoV-2 on chip

…, ST Wereley, JC Linnes, TL Kinzer-Ursem - Analytica chimica …, 2022 - Elsevier
In 2019 the COVID-19 pandemic, caused by SARS-CoV-2, demonstrated the urgent need
for rapid, reliable, and portable diagnostics. The COVID-19 pandemic was declared in …

A smartphone-based particle diffusometry platform for sub-attomolar detection of Vibrio cholerae in environmental water

…, ES Kim, ST Wereley, TL Kinzer-Ursem… - Biosensors and …, 2020 - Elsevier
Each year, 3.4 million people die from waterborne diseases worldwide. Development of a
rapid and portable platform for detecting and monitoring waterborne pathogens would …

[HTML][HTML] Both ligand-and cell-specific parameters control ligand agonism in a kinetic model of g protein–coupled receptor signaling

TL Kinzer-Ursem, JJ Linderman - PLoS computational biology, 2007 - journals.plos.org
G protein–coupled receptors (GPCRs) exist in multiple dynamic states (eg, ligand-bound,
inactive, G protein–coupled) that influence G protein activation and ultimately response …

Selective functionalization of the protein N terminus with N-myristoyl transferase for bioconjugation in cell lysate.

C Kulkarni, TL Kinzer-Ursem… - Chembiochem: a European …, 2013 - europepmc.org
A site to behold: Robust site-specific functionalization of engineered proteins is achieved
with N-myristoyl transferase (NMT) in bacterial cells. NMT tolerates non-natural substrate …

[HTML][HTML] Particle Diffusometry: An Optical Detection Method for Vibrio cholerae Presence in Environmental Water Samples

…, DH Lee, ST Wereley, JC Linnes, TL Kinzer-Ursem - Scientific Reports, 2019 - nature.com
There is a need for a rapid, robust, and sensitive biosensor to identify low concentrations of
pathogens in their native sample matrix without enrichment or purification. Nucleic acid-…

Dynamics of non-canonical amino acid-labeled intra-and extracellular proteins in the developing mouse

AM Saleh, KR Jacobson, TL Kinzer-Ursem… - Cellular and Molecular …, 2019 - Springer
Introduction Mapping protein synthesis and turnover during development will provide insight
into functional tissue assembly; however, quantitative in vivo characterization has been …