User profiles for T. N. Petersen

Thomas Nordahl Petersen

DTU Food, National Food Institute, Denmark
Verified email at food.dtu.dk
Cited by 17859

SignalP 4.0: discriminating signal peptides from transmembrane regions

TN Petersen, S Brunak, G Von Heijne, H Nielsen - Nature methods, 2011 - nature.com
To the Editor: The secretory signal peptide is a ubiquitous proteinsorting signal that targets
its passenger protein for translocation across the endoplasmic reticulum membrane in …

SignalP 5.0 improves signal peptide predictions using deep neural networks

…, KD Tsirigos, CK Sønderby, TN Petersen… - Nature …, 2019 - nature.com
Signal peptides (SPs) are short amino acid sequences in the amino terminus of many newly
synthesized proteins that target proteins into, or across, membranes. Bioinformatic tools can …

[HTML][HTML] A generic method for assignment of reliability scores applied to solvent accessibility predictions

B Petersen, TN Petersen, P Andersen, M Nielsen… - BMC structural …, 2009 - Springer
Background Estimation of the reliability of specific real value predictions is nontrivial and the
efficacy of this is often questionable. It is important to know if you can trust a given prediction …

[HTML][HTML] Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage

…, MP Koopmans, H Vigre, TN Petersen… - Nature …, 2019 - nature.com
Antimicrobial resistance (AMR) is a serious threat to global public health, but obtaining
representative data on AMR for healthy human populations is difficult. Here, we use …

Detection of mobile genetic elements associated with antibiotic resistance in Salmonella enterica using a newly developed web tool: MobileElementFinder

…, FM Aarestrup, AP Roberts, TN Petersen - Journal of …, 2021 - academic.oup.com
Objectives Antimicrobial resistance (AMR) in clinically relevant bacteria is a growing threat
to public health globally. In these bacteria, antimicrobial resistance genes are often …

Improved metagenome binning and assembly using deep variational autoencoders

…, LJ Jensen, HB Nielsen, TN Petersen… - Nature …, 2021 - nature.com
Despite recent advances in metagenomic binning, reconstruction of microbial species from
metagenomics data remains challenging. Here we develop variational autoencoders for …

CPHmodels-3.0—remote homology modeling using structure-guided sequence profiles

…, C Lundegaard, O Lund, TN Petersen - Nucleic acids …, 2010 - academic.oup.com
CPHmodels-3.0 is a web server predicting protein 3D structure by use of single template
homology modeling. The server employs a hybrid of the scoring functions of CPHmodels-2.0 …

[HTML][HTML] Genomic analysis of sewage from 101 countries reveals global landscape of antimicrobial resistance

P Munk, C Brinch, FD Møller, TN Petersen… - Nature …, 2022 - nature.com
Antimicrobial resistance (AMR) is a major threat to global health. Understanding the emergence,
evolution, and transmission of individual antibiotic resistance genes (ARGs) is essential …

Abundance and diversity of the faecal resistome in slaughter pigs and broilers in nine European countries

…, H Schmitt, AD Garcia, RB Hansen, TN Petersen… - Nature …, 2018 - nature.com
Antimicrobial resistance (AMR) in bacteria and associated human morbidity and mortality is
increasing. The use of antimicrobials in livestock selects for AMR that can subsequently be …

[PDF][PDF] The crystal structure of rhamnogalacturonase A from Aspergillus aculeatus: a right-handed parallel β helix

TN Petersen, S Kauppinen, S Larsen - Structure, 1997 - cell.com
Background: Pectic substances are the major polysaccharide components of the middle
lamella and primary cell wall of dicotyledonous plants. They consist of homogalacturonan ‘…