User profiles for T. R. Powell

Timothy Powell

Lecturer, King's College London
Verified email at kcl.ac.uk
Cited by 1469

The inflammatory cytokines: molecular biomarkers for major depressive disorder?

…, KE Tansey, LC Schalkwyk, TR Powell - Biomarkers in …, 2015 - Future Medicine
… However, Powell and colleagues found no association between changes in IL6 mRNA and
response to escitalopram [16], nor did Tsao and colleagues find an association between IL6 …

Depression‐related behavioral tests

TR Powell, C Fernandes… - Current protocols in …, 2012 - Wiley Online Library
Overlapping characteristics between human depressive phenotypes and mouse behaviors
has led to the creation of mouse models that aim to investigate the pathophysiology and …

Inflammatory profiles of severe treatment-resistant depression

R Strawbridge, J Hodsoll, TR Powell, M Hotopf… - Journal of affective …, 2019 - Elsevier
Background Treatment-resistant depression (TRD) contributes substantially to the burden of
mood disorders and is undoubtedly an important subpopulation in whom there are clear …

[HTML][HTML] Telomere length and bipolar disorder

TR Powell, D Dima, S Frangou, G Breen - Neuropsychopharmacology, 2018 - nature.com
Variation in telomere length is heritable and is currently considered a promising biomarker
of susceptibility for neuropsychiatric disorders, particularly because of its association with …

Interferon-γ signaling in human iPSC–derived neurons recapitulates neurodevelopmental disorder phenotypes

…, G McAlonan, E Loth, D Murphy, TR Powell… - Science …, 2020 - science.org
Maternal immune activation increases the risk of neurodevelopmental disorders. Elevated
cytokines, such as interferon-γ (IFN-γ), in offspring’s brains play a central role. IFN-γ activates …

Tumor necrosis factor and its targets in the inflammatory cytokine pathway are identified as putative transcriptomic biomarkers for escitalopram response

TR Powell, LC Schalkwyk, AL Heffernan… - European …, 2013 - Elsevier
Powell is funded by a Medical Research Council PhD studentship. … Powell was involved
in the majority of the laboratory work, in data collection, analysis and in writing the manuscript. …

[HTML][HTML] DNA methylation in interleukin-11 predicts clinical response to antidepressants in GENDEP

TR Powell, RG Smith, S Hackinger… - Translational …, 2013 - nature.com
Transcriptional differences in interleukin-11 (IL11) after antidepressant treatment have been
found to correspond to clinical response in major depressive disorder (MDD) patients. …

[HTML][HTML] The polygenic nature of telomere length and the anti-ageing properties of lithium

…, S de Jong, CM Lewis, D Dima, TR Powell - …, 2019 - nature.com
Telomere length is a promising biomarker for age-related disease and a potential anti-ageing
drug target. Here, we study the genetic architecture of telomere length and the …

Neurological involvement and characterization in acquired hemophagocytic lymphohistiocytosis in adulthood

SM Gratton, TR Powell, BJ Theeler, JS Hawley… - Journal of the …, 2015 - Elsevier
Powell, Theeler, and Hawley report no conflicts of interest. They are active duty medical
officers in the United States Army. The views represented in the paper are the opinions of the …

Judiciality of Minimum-Wage Legislation

TR Powell - Harv. L. Rev., 1923 - HeinOnline
This constitutional question finds no answer in the Constitution. While the legislation, like
substantially all legislation and all law, involves a deprivation of liberty or property, such …