[HTML][HTML] A human proteome detection and quantitation project

NL Anderson, NG Anderson, TW Pearson… - Molecular & Cellular …, 2009 - ASBMB
The lack of sensitive, specific, multiplexable assays for most human proteins is the major
technical barrier impeding development of candidate biomarkers into clinically useful tests. …

Mass-spectrometry-based clinical proteomics–a review and prospective

CE Parker, TW Pearson, NL Anderson, CH Borchers - Analyst, 2010 - pubs.rsc.org
… Terry Pearson Dr Pearson received his BSc and PhD degrees from the University of
British Columbia in Vancouver. After post-doctoral training at the Medical Research Council …

Mass spectrometric quantitation of peptides and proteins using Stable Isotope Standards and Capture by Anti-Peptide Antibodies (SISCAPA)

…, DB Hardie, RW Olafson, TW Pearson - Journal of proteome …, 2004 - ACS Publications
… supports by flow cytometry (see the preceding paper by Pearson et al.). Because no Cys-…
of the immunoadsorbents are described in detail in the preceding paper in Pearson et al. …

Precision of heavy–light peptide ratios measured by MALDI-TOF mass spectrometry

NL Anderson, M Razavi, TW Pearson… - Journal of proteome …, 2012 - ACS Publications
We have investigated the precision of peptide quantitation by MALDI-TOF mass spectrometry
(MS) using six pairs of proteotypic peptides (light) and same-sequence stable isotope …

Procyclin gene expression and loss of the variant surface glycoprotein during differentiation of Trypanosoma brucei.

I Roditi, H Schwarz, TW Pearson, RP Beecroft… - The Journal of cell …, 1989 - rupress.org
… K, and TW Pearson. 1987. Detection of circulating trypanosomal antigens by double antibody
ELISA … Masterson, RP Beecroft, JP Richardson, and TW Pearson. 1989. Expression of …

[HTML][HTML] Interlaboratory evaluation of automated, multiplexed peptide immunoaffinity enrichment coupled to multiple reaction monitoring mass spectrometry for …

…, NL Anderson, SJ Skates, TW Pearson… - Molecular & cellular …, 2012 - ASBMB
The inability to quantify large numbers of proteins in tissues and biofluids with high precision,
sensitivity, and throughput is a major bottleneck in biomarker studies. We previously …

Naturally occurring levels of dimethyl sulfoxide in selected fruits, vegetables, grains, and beverages

TW Pearson, HJ Dawson… - Journal of Agricultural and …, 1981 - ACS Publications
At present, there are only limited reports of Me2SO in nature. Me2SO has been found in
spearmint oil (Canova, 1971), nonfat dry milk (Ferretti and Flanagan, 1972), com (Boyko et al., …

[HTML][HTML] Evaluation of large scale quantitative proteomic assay development using peptide affinity-based mass spectrometry

…, ME Pope, M Razavi, NL Anderson, TW Pearson… - Molecular & cellular …, 2011 - ASBMB
Stable isotope standards and capture by antipeptide antibodies (SISCAPA) couples affinity
enrichment of peptides with stable isotope dilution and detection by multiple reaction …

[HTML][HTML] SISCAPA Peptide Enrichment on Magnetic Beads Using an In-line Bead Trap Device* S

…, D Smith, D Hardie, C Borchers, TW Pearson - Molecular & Cellular …, 2009 - ASBMB
A SISCAPA (stable isotope standards and capture by anti-peptide antibodies) method for
specific antibody-based capture of individual tryptic peptides from a digest of whole human …

Synchronous differentiation of Trypanosoma brucei from bloodstream to procyclic forms in vitro

…, M Quinten, H Schwarz, TW Pearson… - European journal of …, 1990 - Wiley Online Library
The differentiation of mammalian stage Trypanosoma brucei bloodstream forms comprising
predominantly parasites of intermediate and stumpy morphology to the procyclic forms …