User profiles for T. Botta-Orfila
Teresa Botta-OrfilaIDIBAPS-Hospital Clínic Biobank Verified email at crg.eu Cited by 937 |
Identification of blood serum micro‐RNAs associated with idiopathic and LRRK2 Parkinson's disease
Blood‐cell‐free circulating micro‐RNAs (miRNAs) have been proposed as potential accessible
biomarkers for neurodegenerative diseases such as Parkinson's disease (PD). Here we …
biomarkers for neurodegenerative diseases such as Parkinson's disease (PD). Here we …
A preliminary study of the whole-genome expression profile of sporadic and monogenic early-onset Alzheimer's disease
A Antonell, A Lladó, J Altirriba, T Botta-Orfila… - Neurobiology of …, 2013 - Elsevier
Alzheimer's disease (AD) is the most common neurodegenerative dementia. Approximately
10% of cases present at an age of onset before 65 years old, which in turn can be …
10% of cases present at an age of onset before 65 years old, which in turn can be …
MicroRNA alterations in iPSC-derived dopaminergic neurons from Parkinson disease patients
E Tolosa, T Botta-Orfila, X Morató, C Calatayud… - Neurobiology of …, 2018 - Elsevier
… Author links open overlay panel Eduard Tolosa a b , Teresa Botta-Orfila c d , Xavier Morató
e f , Carles Calatayud g , Raquel Ferrer-Lorente h i , María-José Martí a b , Manel Fernández …
e f , Carles Calatayud g , Raquel Ferrer-Lorente h i , María-José Martí a b , Manel Fernández …
[PDF][PDF] An integrative study of protein-RNA condensates identifies scaffolding RNAs and reveals players in fragile X-associated tremor/ataxia syndrome
Recent evidence indicates that specific RNAs promote the formation of ribonucleoprotein
condensates by acting as scaffolds for RNA-binding proteins (RBPs). We systematically …
condensates by acting as scaffolds for RNA-binding proteins (RBPs). We systematically …
Discovering the 3′ UTR-mediated regulation of alpha-synuclein
D Marchese, T Botta-Orfila, D Cirillo… - Nucleic acids …, 2017 - academic.oup.com
… A Student's t-test was performed to assess for significant differences of RNA decay rate …
level with a 0.63 and 0.5 fold-change respectively (Student's t-test, P-value < 0.01, Figure 5A–C). …
level with a 0.63 and 0.5 fold-change respectively (Student's t-test, P-value < 0.01, Figure 5A–C). …
Neuronal intranuclear (hyaline) inclusion disease and fragile X-associated tremor/ataxia syndrome: a morphological and molecular dilemma
E Gelpi, T Botta-Orfila, L Bodi, S Marti, G Kovacs… - Brain, 2017 - academic.oup.com
… Teresa Botta-Orfila … *Ellen Gelpi and Teresa Botta-Orfila authors contributed equally to
this work. … *Ellen Gelpi and Teresa Botta-Orfila authors contributed equally to this work. …
this work. … *Ellen Gelpi and Teresa Botta-Orfila authors contributed equally to this work. …
Long non‐coding RNA uc. 291 controls epithelial differentiation by interfering with the ACTL6A/BAF complex
… role of UC‐containing lncRNAs (T‐UCRs) in … T‐UCR expression profiles of undifferentiated
proliferating keratinocytes with those of differentiated keratinocytes (Fig 1A). We found 79 T‐…
proliferating keratinocytes with those of differentiated keratinocytes (Fig 1A). We found 79 T‐…
Molecular pathophysiology of fragile X-associated tremor/ataxia syndrome and perspectives for drug development
Fragile X-associated tremor/ataxia syndrome (FXTAS) is an inherited neurodegenerative
disorder manifesting in carriers of 55 to 200 CGG repeats in the 5′ untranslated region (UTR) …
disorder manifesting in carriers of 55 to 200 CGG repeats in the 5′ untranslated region (UTR) …
Cerebrospinal fluid levels of coenzyme Q10 are reduced in multiple system atrophy
…, MJ Martí, A Ávila, À Bayés, T Botta-Orfila… - Parkinsonism & related …, 2018 - Elsevier
Introduction The finding of mutations of the COQ2 gene and reduced coenzyme Q10 levels
in the cerebellum in multiple system atrophy (MSA) suggest that coenzyme Q10 is relevant to …
in the cerebellum in multiple system atrophy (MSA) suggest that coenzyme Q10 is relevant to …
[HTML][HTML] Neurodegeneration and cancer: where the disorder prevails
It has been reported that genes up-regulated in cancer are often down-regulated in
neurodegenerative disorders and vice versa. The fact that apparently unrelated diseases share …
neurodegenerative disorders and vice versa. The fact that apparently unrelated diseases share …