Genome-wide atlas of gene expression in the adult mouse brain

…, CN Dang, S Datta, NR Dee, AL Desaki, T Desta… - Nature, 2007 - nature.com
Molecular approaches to understanding the functional circuitry of the nervous system
promise new insights into the relationship between genes, brain and behaviour. The cellular …

[PDF][PDF] Integrated morphoelectric and transcriptomic classification of cortical GABAergic cells

…, N Dee, T Desta, SD Lee, N Dotson, T Egdorf… - Cell, 2020 - cell.com
Neurons are frequently classified into distinct types on the basis of structural, physiological,
or genetic attributes. To better constrain the definition of neuronal cell types, we …

[HTML][HTML] Human neocortical expansion involves glutamatergic neuron diversification

…, T Desta, SD Lee, F D'Orazi, N Dotson, T Egdorf… - Nature, 2021 - nature.com
… for all reconstructed cells from each t-type. b, Intrinsic electrophysiology responses by t-type. …
of all neurons in that t-type, dashed grey line is a global mean of the other t-types. Top row: …

[HTML][HTML] Living with COVID-19-triggered pseudoscience and conspiracies

TT Desta, T Mulugeta - International journal of public health, 2020 - Springer
Objective This piece of work proposes a way for the wise management of pseudoscience
and conspiracy theories. Methods This work encompassed a review of relevant literature and …

An anatomic transcriptional atlas of human glioblastoma

…, M Chapin, S Datta, N Dee, T Desta, T Dolbeare… - Science, 2018 - science.org
… Hansen from Swedish Research Institute for help with patient consent and clinical data
collection; T. Crossley for help with the ivygap.org website; P. Sonpatki for help with …

Classification of electrophysiological and morphological neuron types in the mouse visual cortex

…, TL Daigle, R Dalley, N Dee, T Desta… - Nature …, 2019 - nature.com
… using the t-distributed stochastic neighbor embedding (t-SNE) … saw relatively little overlap in
the t-SNE projection. Conversely… were also largely coherent in the t-SNE projection (Fig. 2h). …

Routine health management information system data in Ethiopia: consistency, trends, and challenges

…, T Bishaw, E Cherinet, M Dereje, TH Desta… - Global health …, 2021 - Taylor & Francis
Background: Ethiopia is investing in the routine Health Management Information System.
Improved routine data are needed for decision-making in the health sector. Objective: To …

A comprehensive transcriptional map of primate brain development

…, A Carey, S Cate, M Chapin, J Chen, N Dee, T Desta… - Nature, 2016 - nature.com
The transcriptional underpinnings of brain development remain poorly understood,
particularly in humans and closely related non-human primates. We describe a high-resolution …

Diabetes enhances periodontal bone loss through enhanced resorption and diminished bone formation

R Liu, HS Bal, T Desta, N Krothapalli… - Journal of dental …, 2006 - journals.sagepub.com
Using a ligature-induced model in type-2 Zucker diabetic fatty (ZDF) rat and normoglycemic
littermates, we investigated whether diabetes primarily affects periodontitis by enhancing …

Diabetes causes decreased osteoclastogenesis, reduced bone formation, and enhanced apoptosis of osteoblastic cells in bacteria stimulated bone loss

H He, R Liu, T Desta, C Leone, LC Gerstenfeld… - …, 2004 - academic.oup.com
The most common cause of inflammatory bone loss is periodontal disease. After bacterial
insult, inflammation induces bone resorption, which is followed by new reparative bone …