[HTML][HTML] Alternative splicing of jnk1a in zebrafish determines first heart field ventricular cardiomyocyte numbers through modulation of hand2 expression
A Santos-Ledo, S Washer, T Dhanaseelan, L Eley… - PLoS …, 2020 - journals.plos.org
The planar cell polarity pathway is required for heart development and whilst the functions
of most pathway members are known, the roles of the jnk genes in cardiac morphogenesis …
of most pathway members are known, the roles of the jnk genes in cardiac morphogenesis …
[HTML][HTML] Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves
…, JE Turner, J Yu, A Alqahtani, T Dhanaseelan… - PLoS …, 2023 - journals.plos.org
Abnormalities of the arterial valves, including bicuspid aortic valve (BAV) are amongst the
most common congenital defects and are a significant cause of morbidity as well as …
most common congenital defects and are a significant cause of morbidity as well as …
[HTML][HTML] Visualization of macrophage subsets in the development of the fetal human inner ear
Background Human inner ear contains macrophages whose functional role in early development
is yet unclear. Recent studies describe inner ear macrophages act as effector cells of …
is yet unclear. Recent studies describe inner ear macrophages act as effector cells of …
Exercise, programmed cell death and exhaustion of cardiomyocyte proliferation in aging zebrafish
…, A Santos-Ledo, T Dhanaseelan… - Disease models & …, 2021 - journals.biologists.com
Exercise may ameliorate the eventual heart failure inherent in human aging. In this study,
we use zebrafish to understand how aging and exercise affect cardiomyocyte turnover and …
we use zebrafish to understand how aging and exercise affect cardiomyocyte turnover and …
[HTML][HTML] Deciphering the spatiotemporal transcriptional and chromatin accessibility of human retinal organoid development at the single-cell level
…, A Unsworth, R Hussain, J Coxhead, T Dhanaseelan… - Iscience, 2024 - Elsevier
Molecular information on the early stages of human retinal development remains scarce due
to limitations in obtaining early human eye samples. Pluripotent stem cell-derived retinal …
to limitations in obtaining early human eye samples. Pluripotent stem cell-derived retinal …
Outcomes of manual small incision cataract surgery in hypermature/morgagnian cataract
JS Christy, T Dhanaseelan… - Journal of Cataract & …, 2023 - journals.lww.com
Purpose: To evaluate the visual outcome and complication rate of manual small incision
cataract surgery (MSICS) in hypermature morgagnian cataract (HMC). Setting: Aravind Eye …
cataract surgery (MSICS) in hypermature morgagnian cataract (HMC). Setting: Aravind Eye …
Spatiotemporal single cell analyses reveal a transient population of retinal progenitor cells in the ciliary margin of developing human retina
…, M Crossier, R Hussain, J Coxhead, T Dhanaseelan… - 2023 - researchsquare.com
The emergence of retinal progenitor cells (RPCs) and differentiation to various retinal cell
types represent fundamental processes during retinal development. Herein, we provide a …
types represent fundamental processes during retinal development. Herein, we provide a …
[HTML][HTML] Single haptic iris fixation of posterior chamber intraocular lens
VR Vivekanandan, T Dhanaseelan… - Indian Journal of …, 2023 - journals.lww.com
Single haptic iris fixation technique is used where there is a loss of 6 clock hours anterior
capsular support. It helps the anterior segment surgeon to fix the intraocular lens to the iris on …
capsular support. It helps the anterior segment surgeon to fix the intraocular lens to the iris on …
[HTML][HTML] Retrospective analysis of the role of anterior segment optical coherence tomography and outcomes of cataract surgery in posterior polar cataract
T Dhanaseelan, A Odayappan… - Indian Journal of …, 2023 - journals.lww.com
Purpose: To evaluate the visual and surgical outcomes of cataract surgery in patients with
posterior polar cataract (PPC) and to evaluate the benefits of preoperative anterior segment …
posterior polar cataract (PPC) and to evaluate the benefits of preoperative anterior segment …
Reply: Outcomes of manual small incision cataract surgery in hypermature morgagnian cataract
J Christy, T Dhanaseelan… - Journal of Cataract & …, 2022 - journals.lww.com
morgagnian cataract. This has given us an opportunity to discuss the nuances in
capsulorhexis which is a crucial step in hypermature cataract surgery. The progression of a …
capsulorhexis which is a crucial step in hypermature cataract surgery. The progression of a …