User profiles for T. Fryland
 | Tue FrylandDepartment of Biomedicin, Århus University Verified email at biomed.au.dk Cited by 267 |
[HTML][HTML] Dominant-negative SERPING1 variants cause intracellular retention of C1 inhibitor in hereditary angioedema
…, I Rose, KA Skipper, T Fryland… - The Journal of …, 2019 - Am Soc Clin Investig
Hereditary angioedema (HAE) is an autosomal dominant disease characterized by recurrent
edema attacks associated with morbidity and mortality. HAE results from variations in the …
edema attacks associated with morbidity and mortality. HAE results from variations in the …
[HTML][HTML] Identification of the BRD1 interaction network and its impact on mental disorder risk
Background The bromodomain containing 1 (BRD1) gene has been implicated with
transcriptional regulation, brain development, and susceptibility to schizophrenia and bipolar …
transcriptional regulation, brain development, and susceptibility to schizophrenia and bipolar …
The schizophrenia-associated BRD1 gene regulates behavior, neurotransmission, and expression of schizophrenia risk enriched gene sets in mice
…, V Paternoster, EM Füchtbauer, J Pallesen, T Fryland… - Biological …, 2017 - Elsevier
… The t test was applied to compare BRD1 expression between groups. (C) Dual luciferase
reporter assay of BRD1 promoter fragments containing rs138880 single nucleotide …
reporter assay of BRD1 promoter fragments containing rs138880 single nucleotide …
The Schizophrenia and Bipolar Disorder associated BRD1 gene is regulated upon chronic restraint stress
Recent genetic evidence has implicated the bromodomain containing 1 gene (BRD1) with
brain development and susceptibility to Schizophrenia and Bipolar Disorder. The BRD1 …
brain development and susceptibility to Schizophrenia and Bipolar Disorder. The BRD1 …
[HTML][HTML] EWS and FUS bind a subset of transcribed genes encoding proteins enriched in RNA regulatory functions
Background FUS (TLS) and EWS (EWSR1) belong to the FET-protein family of RNA and DNA
binding proteins. FUS and EWS are structurally and functionally related and participate in …
binding proteins. FUS and EWS are structurally and functionally related and participate in …
[HTML][HTML] The psychiatric risk gene BRD1 modulates mitochondrial bioenergetics by transcriptional regulation
… to the manufacturer’s recommendations: time point T 3 for interval 1 (baseline), time point T
4 for interval 2 (FCCP or Oligomycin), time point T 9 for interval 3 (rotenone/antimycin A). Cell …
4 for interval 2 (FCCP or Oligomycin), time point T 9 for interval 3 (rotenone/antimycin A). Cell …
Brain proteome changes in female Brd1+/− mice unmask dendritic spine pathology and show enrichment for schizophrenia risk
Genetic and molecular studies have implicated the Bromodomain containing 1 (BRD1) gene
in the pathogenesis of schizophrenia and bipolar disorder. Accordingly, mice heterozygous …
in the pathogenesis of schizophrenia and bipolar disorder. Accordingly, mice heterozygous …
Electroconvulsive seizures regulates the Brd1 gene in the frontal cortex and hippocampus of the adult rat
… For convenience we define the term Brd1-T (Brd1-Total) as any splice variant containing
the exon 4–5 boundary since we find no database annotations indicating exon 4–5 deprived …
the exon 4–5 boundary since we find no database annotations indicating exon 4–5 deprived …
Further immunohistochemical characterization of BRD1 a new susceptibility gene for schizophrenia and bipolar affective disorder
…, IML Olsen, J Pallesen, M Nyegaard, T Fryland… - Brain Structure and …, 2009 - Springer
We have recently shown that the gene BRD1 is associated with schizophrenia and bipolar
affective disorder and that the BRD1 protein (BRD1) which is expressed in neurons may …
affective disorder and that the BRD1 protein (BRD1) which is expressed in neurons may …
[HTML][HTML] Synergistic effect of serotonin 1A and serotonin 1B/D receptor agonists in the treatment of L-DOPA-induced dyskinesia in 6-hydroxydopamine-lesioned rats
M Thomsen, A Stoica, KV Christensen, T Fryland… - Experimental …, 2022 - Elsevier
Background The gold standard for symptomatic relief of Parkinson's disease (PD) is L-DOPA.
However, long-term treatment often leads to motor complications such as L-DOPA-induced …
However, long-term treatment often leads to motor complications such as L-DOPA-induced …