User profiles for T. Ganief
Tariq GaniefUCT Verified email at uct.ac.za Cited by 349 |
Structure of the core of the type III secretion system export apparatus
…, J Caesar, T Dietsche, MT Mebrhatu, T Ganief… - Nature structural & …, 2018 - nature.com
Export of proteins through type III secretion systems is critical for motility and virulence of
many major bacterial pathogens. Three putative integral membrane proteins (FliP, FliQ, FliR) …
many major bacterial pathogens. Three putative integral membrane proteins (FliP, FliQ, FliR) …
DRP1 interacts directly with BAX to induce its activation and apoptosis
…, B Ugarte‐Uribe, C Zollo, T Ganief… - The EMBO …, 2022 - embopress.org
The apoptotic executioner protein BAX and the dynamin‐like protein DRP1 co‐localize at
mitochondria during apoptosis to mediate mitochondrial permeabilization and fragmentation. …
mitochondria during apoptosis to mediate mitochondrial permeabilization and fragmentation. …
[HTML][HTML] The translational regulator FMRP controls lipid and glucose metabolism in mice and humans
…, P Bermudez-Martin, A Van Dijck, T Ganief… - Molecular …, 2019 - Elsevier
… For non-normal data, raw data were log-transformed to meet normality criteria prior to
Student's T-test. If sample size n < 8 or if normality was not reached after log-transformation, data …
Student's T-test. If sample size n < 8 or if normality was not reached after log-transformation, data …
[HTML][HTML] Phosphoproteome Study of Escherichia coli Devoid of Ser/Thr Kinase YeaG During the Metabolic Shift From Glucose to Malate
Understanding phosphorylation-mediated regulation of metabolic enzymes, pathways, and
cell phenotypes under metabolic shifts represents a major challenge. The kinases …
cell phenotypes under metabolic shifts represents a major challenge. The kinases …
Bifidobacterium infantis associates with T cell immunity in human infants and is sufficient to enhance antigen-specific T cells in mice
Bacille Calmette-Guerin (BCG) vaccine can elicit good T H 1 responses in neonates. We
hypothesized that the pioneer gut microbiota affects vaccine T cell responses. Infants who are …
hypothesized that the pioneer gut microbiota affects vaccine T cell responses. Infants who are …
[HTML][HTML] Epigenetic activation of O-linked β-N-acetylglucosamine transferase overrides the differentiation blockage in acute leukemia
…, L Haeusser, G Blumenstock, ST Dreher, T Ganief… - …, 2020 - thelancet.com
Background Overriding the differentiation blockage in acute myeloid leukemia (AML) is the
most successful mode-of-action in leukemia therapy – now curing the vast majority of patients …
most successful mode-of-action in leukemia therapy – now curing the vast majority of patients …
[HTML][HTML] Cell Wall Proteomics Reveal Phenotypic Adaption of Drug-Resistant Mycobacterium smegmatis to Subinhibitory Rifampicin Exposure
… To determine whether the downregulation of ABC transporters could be the result of a
response to oxidative stress, we re-analysed the data from a previous study by Ganief et al. (48) …
response to oxidative stress, we re-analysed the data from a previous study by Ganief et al. (48) …
An integrated workflow for enhanced taxonomic and functional coverage of the mouse fecal metaproteome
… Using LFQ intensities, we then performed a t-test to identify which protein groups have
different abundances between the two procedures. Out of 2,589 quantified protein groups, 365 …
different abundances between the two procedures. Out of 2,589 quantified protein groups, 365 …
Quantitative proteomic analysis of HIV‐1 Tat‐induced dysregulation in SH‐SY5Y neuroblastoma cells
… Here, we used t-tests across triplicate biological replicates as the primary means to identify
a set of 407 stably and significantly differentially abundant protein groups for downstream …
a set of 407 stably and significantly differentially abundant protein groups for downstream …
[HTML][HTML] Time-Dependent, HIV-Tat-Induced Perturbation of Human Neurons In Vitro: Towards a Model for the Molecular Pathology of HIV-Associated Neurocognitive …
A significant proportion of human immunodeficiency virus type 1 (HIV)-positive individuals
are affected by the cognitive, motor and behavioral dysfunction that characterizes HIV-…
are affected by the cognitive, motor and behavioral dysfunction that characterizes HIV-…