How do membrane proteins sense water stress?
…, RHE Friesen, PC Moe, T Heide - Molecular …, 2002 - Wiley Online Library
Maintenance of cell turgor is a prerequisite for almost any form of life as it provides a mechanical
force for the expansion of the cell envelope. As changes in extracellular osmolality will …
force for the expansion of the cell envelope. As changes in extracellular osmolality will …
Chapter 17 Uplift and erosion of the greater Barents Sea: impact on prospectivity and petroleum systems
…, TK Hals, T Heide, T Kiryukhina… - Geological Society …, 2011 - lyellcollection.org
A regional net erosion map for the greater Barents Sea shows that the different areas in the
Barents Sea region have been subject to different magnitudes of uplift and erosion. Net …
Barents Sea region have been subject to different magnitudes of uplift and erosion. Net …
Chapter 10 Tectonostratigraphy of the greater Barents Sea: implications for petroleum systems
…, AE Ryseth, GB Larssen, T Heide… - Geological Society …, 2011 - lyellcollection.org
Palaeogeographic and tectono-stratigraphic considerations in the greater Barents Sea show
that the distribution of reservoirs and hydrocarbon source rocks from the Late Palaeozoic to …
that the distribution of reservoirs and hydrocarbon source rocks from the Late Palaeozoic to …
Quantification of subclonal selection in cancer from bulk sequencing data
… t 0 = 0 to be the time when the first transformed cancer cell begins to grow. At a later time t 1 ,
a … fitter subclone that has experienced Γ successful divisions between t 0 and t 1 is therefore …
a … fitter subclone that has experienced Γ successful divisions between t 0 and t 1 is therefore …
[HTML][HTML] Phenotypic plasticity and genetic control in colorectal cancer evolution
J Househam, T Heide, GD Cresswell, I Spiteri… - Nature, 2022 - nature.com
… (t 2 and t 3 , respectively). The increased growth rate of selected subclones was inferred to
be as much as 20 times higher than that of the background clone, and most selected clones …
be as much as 20 times higher than that of the background clone, and most selected clones …
Longitudinal liquid biopsy and mathematical modeling of clonal evolution forecast time to treatment failure in the PROSPECT-C phase II colorectal cancer clinical trial
…, B Werner, G Vlachogiannis, I Spiteri, T Heide… - Cancer discovery, 2018 - AACR
… These dynamics are captured by the equation of $N( t )$. B, The sum the two populations $N(
t )… C, As CEA measurements are a surrogate for the tumor burden $N( t )$, in this illustrative …
t )… C, As CEA measurements are a surrogate for the tumor burden $N( t )$, in this illustrative …
Can we afford integrity by proof-of-work? Scenarios inspired by the Bitcoin currency
Proof-of-Work (PoW), a well-known principle to ration resource access in client-server relations,
is about to experience a renaissance as a mechanism to protect the integrity of a global …
is about to experience a renaissance as a mechanism to protect the integrity of a global …
[HTML][HTML] The co-evolution of the genome and epigenome in colorectal cancer
T Heide, J Househam, GD Cresswell, I Spiteri, C Lynn… - Nature, 2022 - nature.com
… Using the ASCAT equation to describe log 2 [R ratio] values, we took an integer ploidy value
Ψ t in the tumour t as determined by paired deep WGS in each case and searched a range …
Ψ t in the tumour t as determined by paired deep WGS in each case and searched a range …
Subclonal reconstruction of tumors by using machine learning and population genetics
… The measured mutation rate was μ = 9.9 × 10 −10 per base per tumor doubling, subclones
emerged at t = 22 and t = 27, and selection coefficients were s = 1.3 and s = 3, respectively. …
emerged at t = 22 and t = 27, and selection coefficients were s = 1.3 and s = 3, respectively. …
Towards usability guidelines for mobile websites and applications
The market for mobile devices is growing rapidly nowadays. Constant technolog-ical
improvements provide great opportunities for the creation of mobile applica-tions. For the success …
improvements provide great opportunities for the creation of mobile applica-tions. For the success …