User profiles for T. Klecker

Till Klecker

Universität Bayreuth
Verified email at uni-bayreuth.de
Cited by 836

Making connections: interorganelle contacts orchestrate mitochondrial behavior

T Klecker, S Böckler, B Westermann - Trends in cell biology, 2014 - cell.com
Mitochondria are highly dynamic organelles. During their life cycle they frequently fuse and
divide, and damaged mitochondria are removed by autophagic degradation. These …

Pathways shaping the mitochondrial inner membrane

T Klecker, B Westermann - Open Biology, 2021 - royalsocietypublishing.org
Mitochondria are complex organelles with two membranes. Their architecture is determined
by characteristic folds of the inner membrane, termed cristae. Recent studies in yeast and …

Intramitochondrial transport of phosphatidic acid in yeast by a lipid transfer protein

M Connerth, T Tatsuta, M Haag, T Klecker… - Science, 2012 - science.org
Mitochondria are dynamic organelles whose function depends on intramitochondrial
phospholipid synthesis and the supply of membrane lipids from the endoplasmic reticulum. How …

The yeast cell cortical protein Num1 integrates mitochondrial dynamics into cellular architecture

T Klecker, D Scholz, J Förtsch… - Journal of cell …, 2013 - journals.biologists.com
During the cell cycle each organelle has to be faithfully partitioned to the daughter cells.
However, the mechanisms controlling organellar inheritance remain poorly understood. We …

Identification of the endocytic sorting signal recognized by the Art1-Rsp5 ubiquitin ligase complex

EL Guiney, T Klecker, SD Emr - Molecular biology of the cell, 2016 - Am Soc Cell Biol
… We thank all the members of the Emr lab and Maria Klecker for helpful discussions and
comments on the manuscript. This work was supported by a Cornell University Research Grant to …

Cristae-dependent quality control of the mitochondrial genome

…, D Bunk, D Hörl, H Leonhardt, P Walter, T Klecker… - Science …, 2021 - science.org
… P<0.01, t test. (E) Mitochondrial morphology during mating. Mating events … We thank T.
Kautzleben and N. Lebedeva for technical … We thank T. Kautzleben and N. Lebedeva for technical …

Exocyst subunit Exo70B2 is linked to immune signaling and autophagy

…, OK Teh, FA Ditengou, CW Lee, T Klecker… - The Plant …, 2021 - academic.oup.com
During the immune response, activation of the secretory pathway is key to mounting an
effective response, while gauging its output is important to maintain cellular homeostasis. The …

Fusion, fission, and transport control asymmetric inheritance of mitochondria and protein aggregates

S Böckler, X Chelius, N Hock, T Klecker… - Journal of Cell …, 2017 - rupress.org
Partitioning of cell organelles and cytoplasmic components determines the fate of daughter
cells upon asymmetric division. We studied the role of mitochondria in this process using …

Asymmetric inheritance of mitochondria in yeast

T Klecker, B Westermann - Biological Chemistry, 2020 - degruyter.com
Mitochondria are essential organelles of virtually all eukaryotic organisms. As they cannot
be made de novo, they have to be inherited during cell division. In this review, we provide an …

[HTML][HTML] Regulation with cell size ensures mitochondrial DNA homeostasis during cell growth

…, D Bureik, F Thoma, C Osman, T Klecker… - Nature Structural & …, 2023 - nature.com
… Assuming that mtDNA dilution follows an exponential-growth pattern with a doubling time
T, we can then balance replication, degradation, and dilution to obtain \(\frac{{dn}}{{dt}}={k}_{\…