The nervous system governs both ontogeny and oncology. Regulating organogenesis
during development, maintaining homeostasis, and promoting plasticity throughout life, the …

Chronic, pathological pain remains a global health problem and a challenge to basic and
clinical sciences. A major obstacle to preventing, treating, or reverting chronic pain has been …

Chronic pain represents a major challenge to clinical practice and basic science. Excitatory
neurotransmission in somatosensory nociceptive pathways is predominantly mediated by …

AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor channels mediate
the fast component of excitatory postsynaptic currents in the central nervous system. Site-…

Astrocytic brain tumours, including glioblastomas, are incurable neoplasms characterized
by diffusely infiltrative growth. Here we show that many tumour cells in astrocytomas extend …

A network of communicating tumour cells that is connected by tumour microtubes mediates
the progression of incurable gliomas. Moreover, neuronal activity can foster malignant …

Glioblastomas are incurable tumors infiltrating the brain. A subpopulation of glioblastoma
cells forms a functional and therapy-resistant tumor cell network interconnected by tumor …

Odor discrimination times and their dependence on stimulus similarity were evaluated to
test temporal and spatial models of odor representation in mice. In a go/no-go operant …

… Thomas Kuner† and George J. Augustine* Department of … A 25 ms long pulse of 1 mM
GABA was applied at t … Kuner for help with putrescin [0.1 mM], and selenium dioxide [30 …

Diffuse gliomas, particularly glioblastomas, are incurable brain tumours 1 . They are
characterized by networks of interconnected brain tumour cells that communicate via Ca 2+ …