The domestic dog offers a unique opportunity to explore the genetic basis of disease,
morphology and behaviour. Humans share many diseases with our canine companions, making …

We report a high-quality draft sequence of the genome of the horse (Equus caballus). The
genome is relatively repetitive but has little segmental duplication. Chromosomes appear to …

Whole transcriptome sequencing (RNA-seq) has become a standard for cataloguing and
monitoring RNA populations. One of the main bottlenecks, however, is to correctly identify the …

Horses were domesticated from the Eurasian steppes 5,000–6,000 years ago. Since then,
the use of horses for transportation, warfare, and agriculture, as well as selection for desired …

Intense selective pressures applied over short evolutionary time have resulted in homogeneity
within, but substantial variation among, horse breeds. Utilizing this population structure, …

Healthy aging depends on removal of damaged cellular material that is in part mediated by
autophagy. The nutritional status of cells affects both aging and autophagy through as-yet-…

An equine SNP genotyping array was developed and evaluated on a panel of samples
representing 14 domestic horse breeds and 18 evolutionarily related species. More than 54,000 …

The genomic changes underlying both early and late stages of horse domestication remain
largely unknown. We examined the genomes of 14 early domestic horses from the Bronze …

Przewalski's horses (PHs, Equus ferus ssp. przewalskii) were discovered in the Asian steppes
in the 1870s and represent the last remaining true wild horses. PHs became extinct in the …

Mexican and Peruvian hairless dogs and Chinese crested dogs are characterized by missing
hair and teeth, a phenotype termed canine ectodermal dysplasia (CED). CED is inherited …