Oncogenic mutations of PIK3CA in human cancers
The involvement of the PIK3CA gene product p110α, the catalytic subunit of phosphatidylinositol
3-kinase (PI3K), in human cancer has been suggested for over 15 years, and support …
3-kinase (PI3K), in human cancer has been suggested for over 15 years, and support …
The shared and contrasting roles of IL2 and IL15 in the life and death of normal and neoplastic lymphocytes: implications for cancer therapy
TA Waldmann - Cancer immunology research, 2015 - AACR
… , the elimination of autoreactive T cells to generate tolerance to … of T cells, induce the generation
of cytotoxic T lymphocytes (… T cells (Treg) is involved in the elimination of self-reactive T …
of cytotoxic T lymphocytes (… T cells (Treg) is involved in the elimination of self-reactive T …
Requirement for p53 and p21 to Sustain G2 Arrest After DNA Damage
After DNA damage, many cells appear to enter a sustained arrest in the G 2 phase of the cell
cycle. It is shown here that this arrest could be sustained only when p53 was present in the …
cycle. It is shown here that this arrest could be sustained only when p53 was present in the …
Cohesin mutations in human cancer
VK Hill, JS Kim, T Waldman - Biochimica et Biophysica Acta (BBA)-Reviews …, 2016 - Elsevier
Cohesin is a highly-conserved protein complex that plays important roles in sister chromatid
cohesion, chromatin structure, gene expression, and DNA repair. In humans, cohesin is a …
cohesion, chromatin structure, gene expression, and DNA repair. In humans, cohesin is a …
p21 Is Necessary for the p53-mediated G1 Arrest in Human Cancer Cells
… to Robert and Gay Waldman. … Lowe, SW, Schmitt, SW, Sm t,B. k, Osborne, B. A@andJacks@T.
p53 isrequiredfor radiation-induced apoptosis in mouse thymocytes. Nature (Land.), 362: …
p53 isrequiredfor radiation-induced apoptosis in mouse thymocytes. Nature (Land.), 362: …
[HTML][HTML] Disruption of p53 in human cancer cells alters the responses to therapeutic agents
We have examined the effects of commonly used chemotherapeutic agents on human colon
cancer cell lines in which the p53 pathway has been specifically disrupted by targeted …
cancer cell lines in which the p53 pathway has been specifically disrupted by targeted …
Topological Control of p21WAF1/CIP1 Expression in Normal and Neoplastic Tissues
WS El-Deiry, T Tokino, T Waldman, JD Oliner… - Cancer research, 1995 - AACR
… and the region upstream of human p21WA@'t was identified as a 4.5-kb … of these were
three 20—36-bpblocks located 1.3, 1.7, and 2.2 kb upstream of the first exon of human p2lWt@t. …
three 20—36-bpblocks located 1.3, 1.7, and 2.2 kb upstream of the first exon of human p2lWt@t. …
Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21
PRECISE coordination of the S and M phases of the eukaryotic cell cycle is critical not only
for normal cell division, but also for effective growth arrest under conditions of stress. When …
for normal cell division, but also for effective growth arrest under conditions of stress. When …
Verb‐noun collocations in second language writing: A corpus analysis of learners' English
… 5) observed that “students with good ideas often lose marks because they don't know the four
… I don't know this combination at all; I think this is not a frequent combination; I think this is a …
… I don't know this combination at all; I think this is not a frequent combination; I think this is a …
Societal costs of prescription opioid abuse, dependence, and misuse in the United States
HG Birnbaum, AG White, M Schiller, T Waldman… - Pain …, 2011 - academic.oup.com
Objectives. The objective of this study was to estimate the societal costs of prescription opioid
abuse, dependence, and misuse in the United States. Methods. Costs were grouped into …
abuse, dependence, and misuse in the United States. Methods. Costs were grouped into …